31618

Supelco

2-Naphthylamine

analytical standard

Synonym(s):
2-Aminonaphthalene, β-Naphthylamine
Linear Formula:
C10H7NH2
CAS Number:
Molecular Weight:
143.19
Beilstein/REAXYS Number:
3939429
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

analytical standard

form

neat

shelf life

limited shelf life, expiry date on the label

application(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

306 °C (lit.)

mp

111-113 °C (lit.)

density

1.061 g/mL at 25 °C (lit.)

Featured Industry

Cleaning Products
Cosmetics
Food and Beverages
Personal Care

format

neat

SMILES string

Nc1ccc2ccccc2c1

InChI

1S/C10H9N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,11H2

InChI key

JBIJLHTVPXGSAM-UHFFFAOYSA-N

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General description

2-Naphthylamine is a carcinogenic aromatic amine which induces tumor in urinary bladder.

Application

2-Naphthylamine has been used as reference standard during isolation and identification of urinary metabolites using preparative thin-layer chromatography and gas-liquid chromatography/mass spectral analysis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Caution

Restricted to professional users. Attention − Avoid exposure − obtain special instructions before use.

Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 1650 6.1 / PGII

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Metabolic conversion of 1-and 2-nitronaphthalene to 1-and 2-naphthylamine in the rat.
Johnson, Dale E., and Herbert H. Cornish.
Toxicology and Applied Pharmacology, 46.3, 549-553 (1978)
Formation of urothelial and hepatic DNA adducts from carcinogen 2-naphthylamine.
Kadlubar FF
Carcinogenesis, 2(5), 467-470 (1981)
Dylan M Owen et al.
Nature communications, 3, 1256-1256 (2012-12-06)
Lipid microdomains are postulated to regulate many membrane-associated processes but have remained highly controversial. Here we provide the first direct evidence that the plasma membrane of intact, live cells is comprised of a sub-resolution mixture of approximately 76% ordered and...
Joanna M Kwiatek et al.
PloS one, 8(2), e52960-e52960 (2013-02-08)
Visualization and quantification of lipid order is an important tool in membrane biophysics and cell biology, but the availability of environmentally sensitive fluorescent membrane probes is limited. Here, we present the characterization of the novel fluorescent dyes PY3304, PY3174 and...
Keishi Suga et al.
Langmuir : the ACS journal of surfaces and colloids, 29(6), 1899-1907 (2013-01-18)
The effect of cationic liposomes (CLs) on messenger RNA(mRNA) conformation and translation was studied, focusing on membrane heterogeneity. CLs, composed of 1,2-dioleoyl-sn-glycerol-3-phosphocholine/1,2-dioleoyl-3-timethylammonium propane (DOPC/DOTAP) and DOPC/3β-{N-[(N',N'-dimethylamino)ethyl]carbamoyl}cholesterol (DOPC/DC-Ch), inhibited mRNA translation in an Escherichia coli cell-free translation system. Analysis of the...
Protocols
US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)
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