86320

Sigma-Aldrich

Tartronic acid

≥97.0%

Synonym(s):
Hydroxypropanedioic acid, Hydroxymalonic acid
Linear Formula:
HOCH(COOH)2
CAS Number:
Molecular Weight:
120.06
Beilstein/REAXYS Number:
1209791
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

assay

≥97.0%

mp

158-160 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

OC(C(O)=O)C(O)=O

InChI

1S/C3H4O5/c4-1(2(5)6)3(7)8/h1,4H,(H,5,6)(H,7,8)

InChI key

ROBFUDYVXSDBQM-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

hazcat

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

G DuVal et al.
Biochemistry, 24(8), 2067-2072 (1985-04-09)
Some kinetic characteristics of immobilized native mitochondrial malate dehydrogenase dimers and immobilized protomers, prepared by direct immobilization under conditions yielding complete dissociation without substantial unfolding, were compared to those of native soluble enzyme. Enzyme was covalently immobilized to derivatized porous...
J K Hiltunen et al.
Biochimica et biophysica acta, 678(1), 115-121 (1981-11-18)
The mechanism of depletion of tricarboxylic acid cycle intermediates by isolated rat heart mitochondria was studied using hydroxymalonate (an inhibitor of malic enzymes) and mercaptopicolinate (an inhibitor of phosphoenolpyruvate carboxykinase) as tools. Hydroxymalonate inhibited the respiration rate of isolated mitochondria...
Tartronic acid promotes de novo lipogenesis and inhibits CPT-1? by upregulating acetyl-CoA and malonyl-CoA.
Shi, et al.
Life Sciences, 258, 118240-118240 (2020)
Christopher D Evans et al.
The Journal of chemical physics, 152(13), 134705-134705 (2020-04-10)
The oxidation of glycerol under alkaline conditions in the presence of a heterogeneous catalyst can be tailored to the formation of lactic acid, an important commodity chemical. Despite recent advances in this area, the mechanism for its formation is still...
K F Petersen et al.
Metabolism: clinical and experimental, 44(11), 1380-1383 (1995-11-01)
The relative roles of pyruvate kinase and malic enzyme in substrate cycling between pyruvate and oxaloacetate were examined in perfused livers of 24-hour-fasted normal and triiodothyronine (T3)-treated rats using an inhibitor of malic enzyme (hydroxymalonate). Livers were perfused for 60...

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