H3393

Sigma-Aldrich

Heparin sodium salt from porcine intestinal mucosa

Grade I-A, ≥180 USP units/mg

CAS Number:
MDL number:
NACRES:
NA.21

biological source

Porcine intestinal mucosa

Quality Level

type

Grade I-A

form

powder

specific activity

≥180 USP units/mg

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Heparin sodium salt from porcine intestinal mucosa has been supplemented in the medium prepared for insemination of oocytes with spermatozoa. It has been used to check the effect of heparin on FGF21 (fibroblast growth factor 21) signaling.

Packaging

10000, 25000, 50000, 100000, 250000, 500000, 1000000 units in poly bottle

Biochem/physiol Actions

Heparin is mainly responsible for the delay in the coagulation of blood. It enhances the antithrombin-mediated inactivation of proteases in the coagulation pathway.

Recommended products

Elite grade heparin for diagnostic manufacturing is available as product number SRE0027

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

  1. What is the molecular weight of Heparin sodium salt?

    Heparin is a mixture of polyanion chains having molecular weights ranging from 6,000 to 30,000 Daltons, with most chains in the range of 17,000 to 19,000 Daltons.

  2. How much Heparin sodium salt, is used to prevent coagulation?

    We suggest using 20 to 50 units per mL of blood.

  3. What is the best way to sterilize Heparin sodium salt?

    Although solutions may be autoclaved at 121 °C for 5 to 10 minutes, we generally recommend sterile filtration. This is because prolonged autoclaving may have an effect on its activity.  

  4. What concentration of Heparin sodium salt, can I use to inhibit RNAse activity?

    Heparin has been used at concentrations ranging from 100 to 500 μg/mL. This has been reported in the J. Biol. Chem., 248, 2095 (1973).

  5. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  6. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  7. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  8. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

  10. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects.
Xu J et al.
American Journal of Physiology. Endocrinology and Metabolism, 297, E1105-E1105 (2009)
Sheikh Fayaz Ahmad et al.
Molecular neurobiology, 54(6), 4390-4400 (2016-06-28)
Autism is a neurodevelopmental disorder characterized by stereotypic repetitive behaviors, impaired social interactions, and communication deficits. Numerous immune system abnormalities have been described in individuals with autism including abnormalities in the ratio of Th1/Th2/Th17 cells; however, the expression of the...
Benjamin Ziem et al.
Advanced healthcare materials, 5(22), 2922-2930 (2016-09-02)
Efficient inhibition of cell-pathogen interaction to prevent subsequent infection is an urgent but yet unsolved problem. In this study, the synthesis and functionalization of novel multivalent 2D carbon nanosystems as well as their antiviral efficacy in vitro are shown. For...
Bovine immature oocytes acquire developmental competence during meiotic arrest in vitro.
Hashimoto S et al.
Biology of Reproduction, 66, 1696-1696 (2002)
Guidelines for the use of flow cytometry and cell sorting in immunological studies.
Andrea Cossarizza et al.
European journal of immunology, 47(10), 1584-1797 (2017-10-13)
Articles
There are five identified glycosaminoglycan chains (see Figure 1): Hyaluronan is not sulfated, but the other glycosaminoglycan chains contain sulfate substituents at various positions of the chain.
Read More
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
Read More

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service