T7511

Supelco

Tripelennamine hydrochloride

analytical standard

Synonym(s):
2-(Benzyl[2-dimethylaminoethyl]amino)pyridine, Pyribenzamine hydrochloride, N-Benzyl-N′,N′-dimethyl-N-(2-pyridyl)ethylenediamine hydrochloride
Empirical Formula (Hill Notation):
C16H21N3 · HCl
CAS Number:
Molecular Weight:
291.82
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

form

neat

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Cleaning Products
Cosmetics
Food and Beverages
Forensics and Toxicology
Personal Care
Pharmaceutical (small molecule)
Veterinary

format

neat

SMILES string

CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2.Cl

InChI

1S/C16H21N3.ClH/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H

InChI key

FSSICIQKZGUEAE-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

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General description

Tripelennamine hydrochloride is an antihistamine drug, which is used in the treatment of bronchitis, asthma and bronchoconstriction.

Application

Tripelennamine hydrochloride may be used as a reference standard in the determination of tripelennamine hydrochloride in samples of animal feed by gas chromatography (GC) method, wastewater and urine using high performance liquid chromatography (HPLC) method employing fluorescence detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

25 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Certificate of Analysis
Certificate of Origin
Trace determination of the antihistamines tripelennamine hydrochloride, thenyldiamine hydrochloride, and chlorothen citrate in admixture in animal feed, human urine, and wastewater by high-pressure liquid chromatography and use of a fluorescence detector.
Thompson TH, et al.
Talanta, 30(4), 251-260 (1983)
C E Johanson et al.
Psychopharmacology, 126(2), 140-146 (1996-07-01)
Twenty volunteers were trained to discriminate between 75 mg tripelennamine (TP) and placebo. During the first four sessions, the drugs were identified prior to ingestion by letter code. During the next six sessions, the procedure was the same except the...
J L Lima et al.
Journal of pharmaceutical and biomedical analysis, 14(8-10), 931-938 (1996-06-01)
The construction and evaluation of tripelennamine conventionally-shaped ion-selective electrodes and tubular detectors for the determination of this compound in pharmaceutical formulations are described. Electrodes with conventional configuration have been constructed without an internal reference solution, using several types of immobilized...
S Sekizawa et al.
Respiration physiology, 112(1), 13-22 (1998-08-08)
The response to histamine of nasal afferents has been studied in guinea pigs by recording the electrical activity of the whole ethmoidal nerve (EN) or that of single units. Guinea pigs were anaesthetized with urethane and breathed through a tracheostomy....
C E Johanson et al.
Experimental and clinical psychopharmacology, 6(4), 427-432 (1998-12-23)
Participants discriminated between tripelennamine and placebo in experiments differing in instructional set. In 1 experiment (SED), participants were told that 1 of the 2 drugs was more sedative-like, and during the other (STIM), 1 was more stimulant-like. During generalization tests...

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