MilliporeSigma
All Photos(6)

V0500

Sigma-Aldrich

L-Valine

reagent grade, ≥98% (HPLC)

Sign Into View Organizational & Contract Pricing

Select a Size

Synonym(s):
(S)-α-Aminoisovaleric acid, L-2-Amino-3-methylbutanoic acid
Linear Formula:
(CH3)2CHCH(NH2)CO2H
CAS Number:
Molecular Weight:
117.15
Beilstein:
1721136
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:

grade

reagent grade

Quality Level

Assay

≥98% (HPLC)

form

powder

technique(s)

thin layer chromatography (TLC): suitable

color

white

mp

295-300 °C (subl.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

SMILES string

CC(C)[C@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1

InChI key

KZSNJWFQEVHDMF-BYPYZUCNSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
94619V0513V4638
L-Valine reagent grade, ≥98% (HPLC)

Sigma-Aldrich

V0500

L-Valine

Essential Grade
L-Valine BioUltra, ≥99.5% (NT)

Sigma-Aldrich

94619

L-Valine

Premium Grade
L-Valine from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

V0513

L-Valine

-
L-Valine

SAFC

V4638

L-Valine

-
assay

≥98% (HPLC)

assay

≥99.5% (NT)

assay

98.5-101.0%

assay

≥98.5%

form

powder

form

powder or crystals

form

powder

form

powder

technique(s)

thin layer chromatography (TLC): suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

color

white

color

white

color

white

color

-

mp

295-300 °C (subl.) (lit.)

mp

295-300 °C (subl.) (lit.)

mp

295-300 °C (subl.) (lit.)

mp

295-300 °C (subl.) (lit.)

Application

  • L-Valine has been used as a standard in thin layer chromatography.
  • It has been used as a supplement in Grace′s antheraea medium for the culture of cells and tissue from invertebrates.
  • It has been used in the preparation of starvation media to study the role of relA gene in antibiotic resistance in E. coli.

Biochem/physiol Actions

Valine is an essential amino acid, involved in the biosynthesis of glutamine and alanine. Valine being a branched-chain amino acid (BCAA) maintains a balance among the BCAAs. L-Valine serves as an energy fuel. Long term deficiency of L-Valine leads to growth failure, organ damage and loss of muscle mass.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 6

1 of 6

L-Serine ReagentPlus®, ≥99% (HPLC)

Sigma-Aldrich

S4500

L-Serine

L-Phenylalanine reagent grade, ≥98%

Sigma-Aldrich

P2126

L-Phenylalanine

L-Alanine ≥98% (TLC)

Sigma-Aldrich

A7627

L-Alanine

DL-Valine ReagentPlus®, ≥99.0% (NT)

Sigma-Aldrich

94640

DL-Valine

L-Isoleucine 99%, FCC, FG

Sigma-Aldrich

W527602

L-Isoleucine

L-Tryptophan reagent grade, ≥98% (HPLC)

Sigma-Aldrich

T0254

L-Tryptophan

On the limited role of relA in kanamycin and amino acid starvation induced stringency and subsequent antibiotic cross-protection in Escherichia coli
Chiang
Journal of Experimental Microbiology and Immunology, 15, 59-63 (2011)
Martin Kohlmeier
Nutrient Metabolism: Structures, Functions, and Genes, 390-390 (2015)
Preparation of several media for the culture of tissues and cells from invertebrates.
Vaughn
TCA Manual, 527-537 (1977)
Zhesi Zhu et al.
Nucleic acids research, 49(1), 177-189 (2020-12-15)
Short-chain acylations of lysine residues in eukaryotic proteins are recognized as essential posttranslational chemical modifications (PTMs) that regulate cellular processes from transcription, cell cycle, metabolism, to signal transduction. Lysine butyrylation was initially discovered as a normal straight chain butyrylation (Knbu).
Zhe Yang et al.
Cell research, 28(10), 1013-1025 (2018-09-14)
Adequate protein intake is crucial for the survival and well-being of animals. How animals assess prospective protein sources and ensure dietary amino acid intake plays a critical role in protein homeostasis. By using a quantitative feeding assay, we show that

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service