59769

Sigma-Aldrich

Micro particles based on polystyrene

size: 500 nm

Synonym(s):
Latex beads from PS
MDL number:
NACRES:
NA.32

Quality Level

form

aqueous suspension

concentration

10% (solids)

particle size

500 nm

density

1.05 g/cm3

storage temp.

2-8°C

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Application

Micro particles based on polystyrene, 500 nM may be derivatized to generate media for applications such as antibody conjugation and use in immunoagglutination assay development or the stabilization of Pickering emulsions. Polystyrene microparticles are useful as potential biodegradable vaccine adjuvants and drug delivery devices.

Analysis Note

For every lot exact values of particle size and standard deviation are determined with an accuracy of 0.01 μm using a Coulter Multisizer.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Elizabeth M Walker et al.
Journal of colloid and interface science, 363(1), 307-313 (2011-08-16)
We have studied polydimethylsiloxane (PDMS)-in-1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF(6)]) Pickering emulsions stabilized by polystyrene microparticles with different surface chemistry. Surprisingly, in contrast to the consensus originating from oil/water Pickering emulsions in which the solid particles equilibrate at the oil-water droplet interfaces and...
Sensitive Mie scattering immunoagglutination assay of porcine reproductive and respiratory syndrome virus (PRRSV) from lung tissue samples in a microfluidic chip.
Song JY, Lee CH, Choi EJ, Kim K, et al.
J. Virol. Methods, 178, 31-38 (2011)
Fiona A Sharp et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(3), 870-875 (2009-01-14)
Many currently used and candidate vaccine adjuvants are particulate in nature, but their mechanism of action is not well understood. Here, we show that particulate adjuvants, including biodegradable poly(lactide-co-glycolide) (PLG) and polystyrene microparticles, dramatically enhance secretion of interleukin-1beta (IL-1beta) by...
Shunmugaperumal Tamilvanan et al.
PDA journal of pharmaceutical science and technology, 62(3), 177-190 (2008-07-30)
The objective of this study is to select a multiple-unit sustained-release formulation and to compare it with both commercial immediate and single unit sustained-release capsules and also to determine whether an in vitro-in vivo correlation exists for single- and multiple-...

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