4-Methylumbelliferyl-β-D-glucuronide hydrate

suitable for fluorescence, ≥99.0% (HPLC)

4-Methylumbelliferyl-β-D-glucopyranosiduronic acid, MUG
Empirical Formula (Hill Notation):
C16H16O9 · xH2O
CAS Number:
Molecular Weight:
352.29 (anhydrous basis)
EC Number:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level


≥99.0% (HPLC)


powder or crystals


≤0.1% free 4-Methylumbelliferone
≤15% water


DMSO: 50 mg/mL, clear, colorless to very faintly yellow


λex 365 nm; λem 445 nm in 0.1 M phosphate pH 6.5


suitable for fluorescence

storage temp.


SMILES string




InChI key


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General description

4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) is a fluorogenic substrate.


4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) has been used:
  • as a β-glucuronidase (GUS) substrate for fluorimetric analysis of reporter gene expression in Arabidopsis thaliana
  • for the fluorimetric assay for GUS activity
  • to measure liposome lysis by n-octylglucoside

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Nathaniel M Butler et al.
Planta, 236(6), 1747-1755 (2012-08-08)
Polypyrimidine tract-binding (PTB) proteins are RNA-binding proteins that target specific RNAs for post-transcriptional processing by binding cytosine/uracil motifs. PTBs have established functions in a range of RNA processes including splicing, translation, stability and long-distance transport. Six PTB-like genes identified in...
R.B. Thompson et al.
Analytical Letters, 18, 1847-1847 (1985)
I George et al.
Canadian journal of microbiology, 47(7), 670-675 (2001-09-08)
Two enzymatic methods based on the measurement of the beta-D-galactosidase activity of total coliforms and the beta-D-glucuronidase activity of Escherichia coli were used to assess coliform levels in wastewater alongside traditional culture-based techniques, which can be biased by the aggregation...
Zeng Tao et al.
Nature plants, 5(4), 424-435 (2019-04-10)
Some overwintering plants acquire competence to flower, after experiencing prolonged cold in winter, through a process termed vernalization. In the crucifer plant Arabidopsis thaliana, prolonged cold induces chromatin-mediated silencing of the potent floral repressor FLOWERING LOCUS C (FLC) by Polycomb...
Jean-Félix Dallery et al.
Journal of experimental botany, 71(10), 2910-2921 (2020-02-02)
Infection of Arabidopsis thaliana by the ascomycete fungus Colletotrichum higginsianum is characterized by an early symptomless biotrophic phase followed by a destructive necrotrophic phase. The fungal genome contains 77 secondary metabolism-related biosynthetic gene clusters, whose expression during the infection process...

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