70420

Sigma-Aldrich

Naphthofluorescein

suitable for fluorescence

Empirical Formula (Hill Notation):
C28H16O5
CAS Number:
Molecular Weight:
432.42
Beilstein/REAXYS Number:
61335
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

pKa 

7.6

mp

189 °C (dec.) (lit.)

solubility

DMF: soluble
DMSO: soluble
H2O: soluble (pH ≥ 8)

fluorescence

λex 594 nm; λem 663 nm in 0.1 M Tris pH 9.0

suitability

suitable for fluorescence

SMILES string

Oc1ccc2c3Oc4c(ccc5cc(O)ccc45)C6(OC(=O)c7ccccc67)c3ccc2c1

InChI

1S/C28H16O5/c29-17-7-9-19-15(13-17)5-11-23-25(19)32-26-20-10-8-18(30)14-16(20)6-12-24(26)28(23)22-4-2-1-3-21(22)27(31)33-28/h1-14,29-30H

InChI key

IXQIUDNVFVTQLJ-UHFFFAOYSA-N

Application

suitable as pH-indicator

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Reference standard. Long-wavelength pH-dependent spectra

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xi

Risk Statement

36/37/38

Safety Statement

26-36

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
O.S. Wolfbeis et al.
Mikrochimica Acta, 108, 133-133 (1992)
Julia Baumann et al.
Experimental cell research, 383(2), 111503-111503 (2019-07-25)
Hypoxic blood-brain barrier (BBB) dysfunction is a common feature of CNS diseases however mechanisms underlying barrier disturbance are still largely unknown. This study investigated the role of transforming growth factor β (TGFβ), a cytokine known to induce expression of the...
Sabrina Amalfi et al.
Journal of virology, 94(21) (2020-08-17)
The baculovirus Autographa californica multiple nucleopolyhedrovirus is an insect virus with a circular double-stranded DNA genome, which, among other multiple biotechnological applications, is used as an expression vector for gene delivery in mammalian cells. Nevertheless, the nonspecific immune response triggered...
Stefanie Norkowski et al.
Cellular and molecular life sciences : CMLS, 75(12), 2273-2289 (2017-12-30)
Effector proteins are key virulence factors of pathogenic bacteria that target and subvert the functions of essential host defense mechanisms. Typically, these proteins are delivered into infected host cells via the type III secretion system (T3SS). Recently, however, several effector...

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