75926

Sigma-Aldrich

Oxonol VI

suitable for fluorescence, ≥95% (UV)

Synonym(s):
1,5-Bis(5-oxo-3-propylisoxazol-4-yl)pentamethine oxonol
Empirical Formula (Hill Notation):
C17H20N2O4
CAS Number:
Molecular Weight:
316.35
MDL number:
PubChem Substance ID:
NACRES:
NA.32
Pricing and availability is not currently available.

Quality Level

assay

≥95% (UV)

solubility

methanol: soluble

fluorescence

λex 523 nm; λem 630 nm in 0.1 M Tris pH 9.0

suitability

suitable for fluorescence

shipped in

wet ice

storage temp.

−20°C

SMILES string

CCCC1=NOC(=O)\C1=C/C=C/C=C/c2c(O)onc2CCC

InChI

1S/C17H20N2O4/c1-3-8-14-12(16(20)22-18-14)10-6-5-7-11-13-15(9-4-2)19-23-17(13)21/h5-7,10-11,20H,3-4,8-9H2,1-2H3/b7-5+,10-6+,13-11-

InChI key

CPHARWHMAGUXDW-PQWGHOHWSA-N

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Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

As an optical indicator for membrane potentials in lipid vesicles

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
R J Clarke et al.
Biochimica et biophysica acta, 981(2), 326-336 (1989-06-06)
A method is described for studying the coupling ratio of the Na+/K+ pump, i.e., the ratio of pump-mediated fluxes of Na+ and K+, in a reconstituted system. The method is based on the comparison of the pump-generated current with the...
F Cornelius
Biochemical and biophysical research communications, 160(2), 801-807 (1989-04-28)
In liposomes with reconstituted shark Na,K-ATPase produced to contain sucrose addition of external Na+ and ATP induce an uncoupled Na+-efflux on inside-out oriented pumps which can be inhibited by digitoxigenin. This flux mode is found to be electrogenic and accompanied...
X Yu et al.
Biophysical journal, 64(4), 1232-1242 (1993-04-01)
The Ca2+ transport adenosine triphosphatase of sarcoplasmic reticulum was reconstituted in unilamellar liposomes prepared by reverse-phase evaporation. The size of the resulting proteoliposomes was similar to that of native sarcoplasmic reticulum vesicles, but their protein content was much lower, with...
J Fumero et al.
Biochimica et biophysica acta, 944(2), 164-176 (1988-10-06)
Differential scanning calorimetry (DSC) has been employed to determine the effect of five commonly employed extrinsic potential-sensitive probes on phase transitions of multilamellar suspensions of L-alpha-dimyristoylphosphatidylcholine (DMPC). At mol% values of less than five, the effect of these probes on...
Potential-sensitive molecular probes in membranes of bioenergetic relevance.
J C Smith
Biochimica et biophysica acta, 1016(1), 1-28 (1990-03-15)

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