82660

Sigma-Aldrich

1-Pyrenedecanoic acid

suitable for fluorescence, ≥98.0% (HPLC)

Synonym(s):
10-(1-Pyrenyl)decanoic acid
Empirical Formula (Hill Notation):
C26H28O2
CAS Number:
Molecular Weight:
372.50
Beilstein/REAXYS Number:
2007670
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level

assay

≥98.0% (HPLC)

fluorescence

λex 340 nm; λem 376 nm in methanol

suitability

suitable for fluorescence

SMILES string

OC(=O)CCCCCCCCCc1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C26H28O2/c27-24(28)12-7-5-3-1-2-4-6-9-19-13-14-22-16-15-20-10-8-11-21-17-18-23(19)26(22)25(20)21/h8,10-11,13-18H,1-7,9,12H2,(H,27,28)

InChI key

PIMKEUIWMFJVNB-UHFFFAOYSA-N

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Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Analysis Note

In addition to the emission maximum at 376 nm, there are lower maxima at 396, 415 and 440 nm.

Other Notes

Anionic membrane probe; Measurement of membrane fluidity of polymorphonuclear leukocytes by flow cytometry; Biosynthetically incorporated into cultured fibroblasts

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Pyrenedecanoic acid and pyrene lecithin.
H J Galla et al.
Methods in enzymology, 72, 471-479 (1981-01-01)
M Masuda et al.
Journal of immunological methods, 96(2), 225-231 (1987-02-11)
A method was established for measuring membrane fluidity of polymorphonuclear leukocytes (PMN) by the excimer-forming lipid technique with pyrenedecanoic acid in flow cytometry. When cells were labeled, the use of 2-25 microM of pyrenedecanoic acid provided similar results. Neither the...
J Radom et al.
Biochimica et biophysica acta, 920(2), 131-139 (1987-07-31)
The lipid metabolism in cultured fibroblasts from multisystemic (type 3) lipid storage myopathy and controls has been studied through pulse-chase experiments using 1-pyrenedecanoic acid as precursor. The uptake of 1-pyrenedecanoic acid was not significantly different in multisystemic lipid storage myopathy...
Amit K Saha et al.
Journal of biomechanics, 52, 83-88 (2017-01-14)
The role of cholesterol content on monocyte biomechanics remains understudied despite the well-established link between cholesterol and monocytes/macrophages in atherosclerosis, and the effect on other cell types. In this work, we have investigated the effect of cholesterol on monocyte deformability...
Amit K Saha et al.
Biophysical journal, 112(7), 1481-1488 (2017-04-14)
Cholesterol is an important risk factor of atherosclerosis, due to its active uptake by monocytes/macrophages. Monocyte recruitment from flowing blood to atherosclerotic foci is the key first step in the development of atherosclerosis. Cholesterol content alters cell membrane stiffness, and...

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