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Katharina Feil et al.
BMC neurology, 17(1), 7-7 (2017-01-11)
Cerebellar ataxia (CA) is a frequent and often disabling condition that impairs motor functioning and impacts on quality of life (QoL). No medication has yet been proven effective for the symptomatic or even causative treatment of hereditary or non-hereditary, non-acquired...
Grant C Churchill et al.
PloS one, 15(2), e0229585-e0229585 (2020-02-29)
The enantiomers of many chiral drugs not only exhibit different pharmacological effects in regard to targets that dictate therapeutic and toxic effects, but are also handled differently in the body due to pharmacokinetic effects. We investigated the pharmacokinetics of the...
Hua Li et al.
Journal of chromatography. A, 1583, 80-87 (2018-11-26)
Modified metabolites play important roles in diagnostic monitoring, oxidative response and physiological regulation. Comprehensive analytical methods are greatly needed for improving the coverage of modified metabolites and studying their physiological function. Here, a novel nontargeted profiling method for mapping modified...

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