A1460

Sigma-Aldrich

1-Adamantaneacetyl-Cys-Gly-Arg-Gly-Asp-Ser-Pro-Cys [Disulfide bridge: 1–8]

≥97% (HPLC)

Empirical Formula (Hill Notation):
C40H61N11O13S2
CAS Number:
Molecular Weight:
968.11
MDL number:

assay

≥97% (HPLC)

storage temp.

−20°C

Biochem/physiol Actions

Inhibits the binding of the integrin α4β1 to the fibronectin connecting segment 1 (CS-1) and to the vascular cell adhesion molecule 1 (VCAM 1).

Certificate of Analysis

Certificate of Origin

P M Cardarelli et al.
The Journal of biological chemistry, 269(28), 18668-18673 (1994-07-15)
The integrin supergene family includes receptors for a variety of extracellular matrix as well as cell surface proteins. Integrin alpha 4 has been shown to play an important role in leukocyte adhesion and extravasation during immune and inflammatory reactions. One...

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