A8138

Sigma-Aldrich

8-(6-Aminohexyl)aminoadenosine 3′:5′-cyclic monophosphate

~98%

Empirical Formula (Hill Notation):
C16H26N7O6P
CAS Number:
Molecular Weight:
443.39
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

~98%

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

NCCCCCCNc1nc2c(N)ncnc2n1[C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O

InChI

1S/C16H26N7O6P/c17-5-3-1-2-4-6-19-16-22-10-13(18)20-8-21-14(10)23(16)15-11(24)12-9(28-15)7-27-30(25,26)29-12/h8-9,11-12,15,24H,1-7,17H2,(H,19,22)(H,25,26)(H2,18,20,21)/t9-,11-,12-,15-/m1/s1

InChI key

WCWLOZYNRVLFOG-SDBHATRESA-N

Application

Cyclic AMP analog which shows partially selective agonist activity with Type I cAMP-dependent protein kinase isozyme.

Packaging

25 mg in poly bottle

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Jong Seol Yuk et al.
Biosensors & bioelectronics, 26(7), 3213-3218 (2011-01-25)
We present a novel approach to the enhancement of surface plasmon-coupled emission (SPCE) using surface plasmon excitation in a bimetal (Ag/Au) layer and we validate the enhancement by presenting the results of a model human IgG immunoassay. Theoretical calculations using...
Jody L Swift et al.
Biointerphases, 5(4), 139-148 (2011-01-12)
Fluorescence microscopy methods including total internal reflection fluorescence and confocal laser scanning microscopy have played a major role in modern cell biology research by permitting imaging of fluorescently tagged macromolecules in living cells. These methods are often used to examine...
Anirban Chakraborty et al.
Methods in enzymology, 472, 19-30 (2010-06-29)
We describe the synthesis of phosphine derivatives of three fluorescent probes that have a brightness and photostability suitable for single-molecule fluorescence spectroscopy and microscopy: Alexa488, Cy3B, and Alexa647. In addition, we describe procedures for use of these reagents in azide-specific...
Alexey V Ulasov et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 19(1), 103-112 (2010-11-04)
We have evaluated the key properties of the polyethylenimine (PEI)-polyethylene glycol (PEG)-TAT peptide polyplex nanoparticles including their behavior in cells and compared them with the transfection efficacy (TE) using 11 different cell lines. We found statistically significant positive correlation between...
Connie S Lebakken et al.
Journal of biomolecular screening, 14(8), 924-935 (2009-07-01)
The expansion of kinase assay technologies over the past decade has mirrored the growing interest in kinases as drug targets. As a result, there is no shortage of convenient, fluorescence-based methods available to assay targets that span the kinome. The...

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