A8138

Sigma-Aldrich

8-(6-Aminohexyl)aminoadenosine 3′:5′-cyclic monophosphate

~98%

Empirical Formula (Hill Notation):
C16H26N7O6P
CAS Number:
Molecular Weight:
443.39
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

~98%

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

NCCCCCCNc1nc2c(N)ncnc2n1[C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O

InChI

1S/C16H26N7O6P/c17-5-3-1-2-4-6-19-16-22-10-13(18)20-8-21-14(10)23(16)15-11(24)12-9(28-15)7-27-30(25,26)29-12/h8-9,11-12,15,24H,1-7,17H2,(H,19,22)(H,25,26)(H2,18,20,21)/t9-,11-,12-,15-/m1/s1

InChI key

WCWLOZYNRVLFOG-SDBHATRESA-N

Application

Cyclic AMP analog which shows partially selective agonist activity with Type I cAMP-dependent protein kinase isozyme.

Packaging

25 mg in poly bottle

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Alexey V Ulasov et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 19(1), 103-112 (2010-11-04)
We have evaluated the key properties of the polyethylenimine (PEI)-polyethylene glycol (PEG)-TAT peptide polyplex nanoparticles including their behavior in cells and compared them with the transfection efficacy (TE) using 11 different cell lines. We found statistically significant positive correlation between...
Connie S Lebakken et al.
Journal of biomolecular screening, 14(8), 924-935 (2009-07-01)
The expansion of kinase assay technologies over the past decade has mirrored the growing interest in kinases as drug targets. As a result, there is no shortage of convenient, fluorescence-based methods available to assay targets that span the kinome. The...
Windy Allman et al.
Cellular immunology, 271(2), 292-298 (2011-08-25)
In myasthenia gravis (MG), the neuromuscular transmission is impaired by antibodies (Abs) specific for muscle acetylcholine receptor (AChR). Anti-AChR Abs can be detected in the serum of MG patients, although their levels do not correlate with disease severity. In this...
Jong Seol Yuk et al.
Biosensors & bioelectronics, 26(7), 3213-3218 (2011-01-25)
We present a novel approach to the enhancement of surface plasmon-coupled emission (SPCE) using surface plasmon excitation in a bimetal (Ag/Au) layer and we validate the enhancement by presenting the results of a model human IgG immunoassay. Theoretical calculations using...
Jody L Swift et al.
Biointerphases, 5(4), 139-148 (2011-01-12)
Fluorescence microscopy methods including total internal reflection fluorescence and confocal laser scanning microscopy have played a major role in modern cell biology research by permitting imaging of fluorescently tagged macromolecules in living cells. These methods are often used to examine...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service