CRKL is a CRK-like protein that activates RAS an Jun kinase signaling pathways.
CRKL is an adaptor protein that associates with several signaling molecules such as c-ABL, PI3-K, SOS, C3G and SOS. Furthermore, CRKL has been implicated in hematopoietic and leukemic signaling pathways.
Rabbit Anti-CRKL antibody associates with canine, human, mouse, and rat CRKL.
The immunogen for anti-CRKL antibody: synthetic peptide derected towards the middle region of human CRKL
Rabbit Anti-CRKL antibody can be used for western blot (2μg/ml) assays.
Synthetic peptide located within the following region: RSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPS
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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