Krüppel-like factor 2 (KLF2) is a multifunction transcriptional regulator with growth-inhibitory, pro-apoptotic and anti-angiogenic activity towards monocytic cells. KLF2 modulates gene expression in endothelial cells. It is a positive regulator of embryonic β-globin gene expression.
Anti-KLF2 polyclonal antibody reacts with human, mouse, rat, and pig Krüppel-like factor 2 proteins.
The immunogen for anti-KLF2 antibody: synthetic peptide derected towards the middle region of human KLF2
Anti-KLF2 polyclonal antibody is used to tag Krüppel-like factor 2 protein for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of Krüppel-like factor 2 in gene expression and cell processes such as growth, differentiation and apoptosis.
Synthetic peptide located within the following region: IPASGPRNPFPPPFGPGPSFGGPGPALHYGPPAPGAFGLFEDAAAAAAAL
Lyophilized from PBS buffer with 2% sucrose
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