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Anti-BMPR2 (836-850) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Anti-BMPR3, Anti-BMPRII, Anti-BMR2, Anti-BRK3, Anti-Bone morphogenetic protein receptor type II precursor (Homo sapiens), Anti-PPH1, Anti-TALK, Anti-TRG10
MDL number:

biological source




antibody form

IgG fraction of antiserum

antibody product type

primary antibodies




buffered aqueous solution

mol wt

antigen ~115 kDa

species reactivity



western blot: 1:500-1:2,000

UniProt accession no.

shipped in

dry ice

storage temp.


Gene Information

human ... BMPR2(659)

General description

Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage, hematopoietic cell formation and mesoderm patterning. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors.


synthetic peptide corresponding to amino acids 836-850 of human BMPR2.


Anti-BMPR2 (836-850) antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500-1:2000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit

Biochem/physiol Actions

Bone Morphogenetic Protein Receptor 2 (BMPR2) is a 70-80kDa protein that belongs to serine/threonine kinases family. BMPs bind to BMPR2 and then recruis the transducing type I receptor, which in turn activates the Smad protein signaling pathway.BMPR2 also plays an essential role in human T-cell differentiation. The loss of interaction and lack of phosphorylation of TCTEL1 by BMPR2 may contribute to the pathogenesis of primary pulmonary hypertension (PPH).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


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