B173

Sigma-Aldrich

BRL 54443 maleate salt

solid

Synonym(s):
3-(1-Methylpiperidin-4-yl)-1H-indol-5-ol maleate salt
Empirical Formula (Hill Notation):
C14H18N2O · C4H4O4
CAS Number:
Molecular Weight:
346.38
MDL number:
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

form

solid

color

white

solubility

H2O: 50 mg/mL

storage temp.

2-8°C

SMILES string

OC(=O)\C=C/C(O)=O.CN1CCC(CC1)c2c[nH]c3ccc(O)cc23

InChI

1S/C14H18N2O.C4H4O4/c1-16-6-4-10(5-7-16)13-9-15-14-3-2-11(17)8-12(13)14;5-3(6)1-2-4(7)8/h2-3,8-10,15,17H,4-7H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

INGCLXPSKXSYND-BTJKTKAUSA-N

Gene Information

human ... HTR1E(3354), HTR1F(3355)

Packaging

10 mg in poly bottle
50 mg in glass bottle

Biochem/physiol Actions

Potent 5-HT1E/1F serotonin receptor agonist.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Caution

Photosensitive

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Effect of BRL 54443 (3-(1-methylpiperidin-4-yl)-1H-indol-5-ol) a 5-HT1E/1F receptor agonist on general behaviour and maximal electroshock seizure threshold in the rat.
Lightowler, et al.
British Journal of Pharmacology, 123, 237P-237P (1998)
BRL 54443 a potent agonist with selectivity for human cloned 5-HT1E and 5-HT1F receptors.
Brown, et al.
British Journal of Pharmacology, 123, 233P-233P (1998)

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