Bombesin acetate salt hydrate

≥97% (HPLC)

Empirical Formula (Hill Notation):
C71H110N24O18S · xC2H4O2 · yH2O
Molecular Weight:
1619.85 (anhydrous free base basis)
Beilstein/REAXYS Number:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level


≥97% (HPLC)

storage temp.


SMILES string




InChI key


Gene Information

human ... GRPR(2925)

Looking for similar products? Visit Product Comparison Guide

Amino Acid Sequence


General description

Gastrin releasing peptide receptor (GRP-R) belongs to the G protein-coupled receptors (GPCR) family. The gene for the gastrin‐releasing peptide receptor is located on the short arm of human X chromosome.


Bombesin acetate salt hydrate has been used in immunohistochemical methods and food intake measurements.


1, 5 mg in glass bottle

Biochem/physiol Actions

Tetradecapeptide originally isolated from the skin of the frog Bombina bombina. Bombesin acts at specific brain nuclei to inhibit food intake. It also increases blood glucose levels.
Bombesin/gastrin releasing peptide (BN/GRP) serves as an autocrine growth factor in small cell lung cancer (SCLC). Overexpression of gastrin releasing peptide receptor (GRP-R) is associated with neuroblastoma tumor aggressiveness. GRP-R modulates the important enzymes, that participates in glucose metabolism. Bombesin, a pulmonary growth factor helps to satisfy the conditions for autocrine stimulation.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Céléna Dubuc et al.
Bioorganic & medicinal chemistry letters, 18(7), 2424-2427 (2008-03-11)
Sulfonated aluminum phthalocyanines (AlPcS) are potent photosensitizers for the photodynamic therapy (PDT) of cancer. In this study we evaluate the possibility to improve the efficacy of AlPcS-PDT for prostate cancer by targeting tetrasulfonated aluminum phthalocyanines (AlPcS(4)) to the gastrin-releasing peptide...
[Psi13, 14] bombesin analogues inhibit growth of small cell lung cancer in vitro and in vivo
Mahmoud S, et al.
Cancer research, 51(7), 1798-1802 (1991)
Silencing gastrin-releasing peptide receptor suppresses key regulators of aerobic glycolysis in neuroblastoma cells
Rellinger E J, et al.
Pediatric Blood & Cancer, 62(4), 581-586 (2015)
Bombesin microinjection into the basolateral amygdala influences feeding behavior in the rat
Vigh J, et al.
Brain Research, 847(2), 253-261 (1999)
S Hossein Fatemi et al.
Cerebellum (London, England), 8(1), 64-69 (2008-11-13)
Autism is a neurodevelopmental disorder that is often comorbid with seizures. Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in brain. GABA(B) receptors play an important role in maintaining excitatory-inhibitory balance in brain and alterations may lead to seizures. We...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon


Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.