C0128

Sigma-Aldrich

α-Chloralose

Synonym(s):
Anhydro-D-glucochloral, 1,2-O-(2,2,2-Trichloroethylidene)-α-D-glucofuranose, Chloralose
Empirical Formula (Hill Notation):
C8H11Cl3O6
CAS Number:
Molecular Weight:
309.53
Beilstein/REAXYS Number:
85418
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

impurities

≤20% β-anomer

solubility

ethanol: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow (or yellow-brown)

SMILES string

OC[C@@H](O)[C@H]1O[C@@H]2O[C@@H](O[C@@H]2[C@H]1O)C(Cl)(Cl)Cl

InChI

1S/C8H11Cl3O6/c9-8(10,11)7-16-5-3(14)4(2(13)1-12)15-6(5)17-7/h2-7,12-14H,1H2/t2-,3+,4-,5-,6-,7-/m1/s1

InChI key

OJYGBLRPYBAHRT-IPQSZEQASA-N

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Related Categories

Application

α-Chloralose has been used as anesthetic in surgical preparations.

Packaging

25, 100, 500 g in poly bottle
1 kg in poly bottle

Biochem/physiol Actions

α-Chloralose is used as an immobilizing agent. It is mostly used in studies, which involves autonomic reflexes. α-Chloralose is a sedative hypnotic. It has high significance as anesthetic for laboratory animals.

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Statements

Target Organs

Central nervous system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Serotonin in the solitary tract nucleus shortens the laryngeal chemoreflex in anaesthetized neonatal rats
Donnelly WT, et al.
Experimental Physiology, 101(7), 946-961 (2016)
Preparation of water-soluble compounds by covalent attachment of solubilizing moieties
The Practice of Medicinal Chemistry, 767-785 (2008)
Vertebrate pest control chemicals and their use in urban and rural environments
Hayes' Handbook of Pesticide Toxicology, 271-284 (2010)
Activation of serotonergic neurons in the medullary caudal raphe shortens the laryngeal chemoreflex in anaesthetized neonatal rats
Donnelly WT, et al.
Experimental Physiology, 102(8), 1007-1018 (2017)
Preanesthesia, anesthesia, analgesia, and euthanasia
Laboratory Animal Medicine, 1135-1200 (2015)

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