C1017

Sigma-Aldrich

Citrinin

from Penicillium citrinum, ≥98% (HPLC)

Synonym(s):
4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid
Empirical Formula (Hill Notation):
C13H14O5
CAS Number:
Molecular Weight:
250.25
Beilstein/REAXYS Number:
5282243
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

biological source

Penicillium citrinum

assay

≥98% (HPLC)

storage temp.

2-8°C

SMILES string

C[C@H]1OC=C2C(O)=C(C(O)=O)C(=O)C(C)=C2[C@@H]1C

InChI

1S/C13H14O5/c1-5-7(3)18-4-8-9(5)6(2)11(14)10(12(8)15)13(16)17/h4-5,7,15H,1-3H3,(H,16,17)/t5-,7-/m1/s1

InChI key

CQIUKKVOEOPUDV-IYSWYEEDSA-N

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Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 3462 6.1 / PGIII

WGK Germany

WGK 3

Petra Patakova
Journal of industrial microbiology & biotechnology, 40(2), 169-181 (2012-11-28)
The genus Monascus, comprising nine species, can reproduce either vegetatively with filaments and conidia or sexually by the formation of ascospores. The most well-known species of genus Monascus, namely, M. purpureus, M. ruber and M. pilosus, are often used for...
Maja Segvić Klarić et al.
Archives of toxicology, 86(1), 97-107 (2011-07-09)
The aim of this study was to establish the involvement of calcium signalling in genotoxicity, apoptosis and necrosis evoked by ochratoxin A (OTA) and citrinin (CTN) alone or in combination in porcine kidney PK15 cells. Cell proliferation test (MTT) and...
Li-Chuan Hsu et al.
Journal of agricultural and food chemistry, 60(32), 7880-7885 (2012-07-28)
Monascus species have traditionally been used in Asian food, with rice as their fermentation substrate. Red mold rice (RMR) contains citrinin, a nephrotoxic agent capable of exerting oxidative stress and cellular apoptosis. We investigated the components in RMR that could...
Yongning Li et al.
Food chemistry, 134(4), 2540-2545 (2013-02-28)
The determination of citrinin (CIT) by a microsphere-based flow cytometric immunoassay (MFCI) has been developed. In the method, the carboxyl-modified microspheres were conjugated with CIT-Ovalbumin (OVA) antigen. CIT competed with the CIT-OVA antigen on the surface of the microspheres for...
Dubravka Flajs et al.
Arhiv za higijenu rada i toksikologiju, 60(4), 457-464 (2010-01-12)
Citrinin (CTN) is a nephrotoxic mycotoxin produced by several fungal strains belonging to the genera Penicillium, Aspergillus, and Monascus. It contaminates various commodities of plant origin, cereals in particular, and is usually found together with another nephrotoxic mycotoxin, ochratoxin A...

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