C106

Sigma-Aldrich

CGS-12066 maleate salt

solid

Synonym(s):
7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-1,2-aquinoxaline maleate salt
Empirical Formula (Hill Notation):
C17H17F3N4 · C4H4O4
CAS Number:
Molecular Weight:
450.41
MDL number:
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.

form

solid

color

white

solubility

H2O: 1.4 mg/mL
ethanol: 1.8 mg/mL
0.1 M HCl: 4 mg/mL

SMILES string

OC(=O)\C=C/C(O)=O.CN1CCN(CC1)c2nc3cc(ccc3n4cccc24)C(F)(F)F

InChI

1S/C17H17F3N4.C4H4O4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16;5-3(6)1-2-4(7)8/h2-6,11H,7-10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

ZBPAHEUAJMCLRD-BTJKTKAUSA-N

Gene Information

human ... HTR1B(3351)

Packaging

25 mg in poly bottle

Biochem/physiol Actions

5-HT1B serotonin receptor agonist.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

3

Certificate of Analysis
Certificate of Origin
Kenji Ohba et al.
PloS one, 9(5), e97787-e97787 (2014-05-27)
High prevalence of infection with high-risk human papilloma virus (HPV) ranging from 25 to 100% (average 31%) was observed in breast cancer (BC) patients in Singapore using novel DNA chip technology. Early stage of BC demonstrated higher HPV positivity, and...
Mattia Bramini et al.
ACS nano, 8(5), 4304-4312 (2014-04-30)
Understanding nanoparticle interactions with the central nervous system, in particular the blood-brain barrier, is key to advances in therapeutics, as well as assessing the safety of nanoparticles. Challenges in achieving insights have been significant, even for relatively simple models. Here...
Marc Cuesta et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(4), 1360-1370 (2014-12-17)
In humans, shift work induces a desynchronization between the circadian system and the outside world, which contributes to shift work-associated medical disorders. Using a simulated night shift experiment, we previously showed that 3 d of bright light at night fully...
Mona Shehata et al.
Breast cancer research : BCR, 16(4), 411-411 (2014-07-25)
Lineage tracing using inducible genetic labeling has emerged to be a powerful method for interrogating the developmental fate of cells in intact tissues. A common induction mechanism is the use of tamoxifen-dependent Cre recombinase (CreER and CreERT2), but the effects...
Brendan M Leung et al.
Journal of tissue engineering and regenerative medicine, 9(11), 1247-1258 (2013-03-19)
Modular cardiac tissues developed both vascular and cardiac structures in vivo, provided that the host response was attenuated by omitting xenoproteins from the modules. Collagen gel modules (with Matrigel(TM)) containing cardiomyocytes (CMs) alone or CMs with surface-seeded endothelial cells (ECs; CM/EC...

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