MilliporeSigma
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C1371

Sigma-Aldrich

Anti-CEBPB (267-279) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):
Anti-C/EBP-β, Anti-CEBPB CCAAT/enhancer-binding protein beta, Anti-CRP2, Anti-IL6DBP, Anti-LAP, Anti-NF-IL6, Anti-TCF5

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~36 kDa

species reactivity

human

technique(s)

western blot: 1:500-1:2,000

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... CEBPB(1051)

Immunogen

synthetic peptide corresponding to amino acids 267-279 of human CEBPB

Application

Anti-CEBPB (267-279) antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500-1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Biochem/physiol Actions

CCAAT/enhancer-binding protein beta is a protein encoded by the CEBPB gene in humans. It is also referred as CRP2, IL6DBP, LAP, NF-IL6 and TCF5. It is a transcription factor that plays a crucial role in survival and transformation of gene in ALK along with anaplastic large cell lymphoma (ALCL). It is involved in the regulation of immune system and inflammatory responses along with other processes. CEBPB expression is essential for infiltrating macrophages for up-regulation of M2-specific genes and muscle regeneration. Its presence in muscle cells does not affect regeneration. It induces cell death in human breast cancer cells and stimulates autophagy.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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