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C6292

Sigma-Aldrich

Monoclonal Anti-Caldesmon antibody produced in mouse

clone CALD-8, ascites fluid

MDL number:

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

CALD-8, monoclonal

contains

15 mM sodium azide

species reactivity

human, pig, rabbit, guinea pig

application(s)

indirect immunofluorescence: suitable using frozen human tissue sections
western blot: 1:400 using pig stomach caldesmon extract

isotype

IgG1

conjugate

unconjugated

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... CALD1(800)

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Specificity

The antibody localizes the high molecular weight form of caldesmon in chicken or turkey gizzard and the low molecular weight form of caldesmon in chicken fibroblasts by immunoblotting. The antibody detects epitopes located on the non-calmodulin-binding part of caldesmon, more specifically, the central region of the molecule.

Immunogen

caldesmon from turkey gizzard

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Certificate of Analysis

Certificate of Origin

M J McManus et al.
Proceedings of the National Academy of Sciences of the United States of America, 94(21), 11351-11356 (1997-10-23)
The avian erythroblastosis viral oncogene (v-erbB) encodes a receptor tyrosine kinase that possesses sarcomagenic and leukemogenic potential. We have expressed transforming and nontransforming mutants of v-erbB in fibroblasts to detect transformation-associated signal transduction events. Coimmunoprecipitation and affinity chromatography have been...
W Durand-Arczynska et al.
Histochemistry, 100(6), 465-471 (1993-12-01)
Calponin and caldesmon are two proteins considered to play a regulatory role in smooth muscle contraction, which have never previously been found to be expressed in subcultured cells. In the present study, immunocytochemistry and immunoblotting were performed to identify these...

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