All Photos(1)

C7230

Sigma-Aldrich

N-[2-(4-(4-Chlorophenyl)piperazin-1-yl)ethyl]-3-methoxybenzamide

solid

Empirical Formula (Hill Notation):
C20H24ClN3O2
Molecular Weight:
373.88
MDL number:
PubChem Substance ID:

form

solid

solubility

DMSO: 22 mg/mL
H2O: insoluble

SMILES string

COc1cccc(c1)C(=O)NCCN2CCN(CC2)c3ccc(Cl)cc3

Biochem/physiol Actions

Potent, selective D4 dopamine receptor ligand.

Certificate of Analysis

Certificate of Origin

R Perrone et al.
Journal of medicinal chemistry, 43(2), 270-277 (2000-01-29)
N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide (1), a high-affinity and selective dopamine D(4) receptor ligand, was chosen as a lead, and structural modifications were done on its amide bond and on its alkyl chain linking the benzamide moiety to the piperazine ring and by preparing

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