E3020

Sigma-Aldrich

(±)-(E)-4-Ethyl-2-(Z)-hydroxyimino-5-nitro-3-hexen-1-yl-nicotinamide

≥97%

Synonym(s):
NOR-4
Empirical Formula (Hill Notation):
C14H18N4O4
CAS Number:
Molecular Weight:
306.32
MDL number:
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.

assay

≥97%

storage temp.

−20°C

SMILES string

CC(N+(O-)=O)/C(CC)=C/C(CNC(C1=CN=CC=C1)=O)=N/O

InChI

1S/C14H18N4O4/c1-3-11(10(2)18(21)22)7-13(17-20)9-16-14(19)12-5-4-6-15-8-12/h4-8,10,20H,3,9H2,1-2H3,(H,16,19)/b11-7+,17-13-

InChI key

KIWSYRHAAPLJFJ-DNZSEPECSA-N

Packaging

10 mg in glass insert

Application

NO donor; releases nitric oxide spontaneously in a rate-controlled manner. Half-life in solution = 60 min.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xi

Risk Statement

36/37/38

Safety Statement

26-36

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Y Kita et al.
European journal of pharmacology, 257(1-2), 123-130 (1994-05-12)
(+-)-(E)-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexeneamide (FK409), which was isolated from microbial products, has been reported to show a vasorelaxant effect through a mechanism similar to that of the organic nitrates such as isosorbide dinitrate. In solution at pH 7.4, FK409 decomposed and released nitric...
Articles
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
Read More

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