E3145

Sigma-Aldrich

3-Ethyl-3-(ethylaminoethyl)-1-hydroxy-2-oxo-1-triazene

≥90%

Synonym(s):
NOC-12
Empirical Formula (Hill Notation):
C6H16N4O2
CAS Number:
Molecular Weight:
176.22
MDL number:
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

assay

≥90%

storage temp.

−20°C

SMILES string

CCNCCN(CC)\N+(O-)=N\O

InChI

1S/C6H16N4O2/c1-3-7-5-6-9(4-2)10(12)8-11/h7,11H,3-6H2,1-2H3/b10-8-

InChI key

DPKCLDSTXVCYSN-NTMALXAHSA-N

Application

Stable complex releases NO under physiological conditions without a cofactor. Half-life in solution = 327 min.

Pictograms

Flame

Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xi

Risk Statement

36/37/38

Safety Statement

26-36

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Tengfang Ling et al.
The Plant cell, 29(11), 2871-2881 (2017-11-01)
Pathogens deliver effectors into plant cells to suppress immunity-related signaling. However, effector recognition by the host elicits a hypersensitive response (HR) that overcomes the inhibition of host signaling networks, restoring disease resistance. Signaling components are shared between the pathogen-associated molecular...
Alana K Majors et al.
PloS one, 13(7), e0200074-e0200074 (2018-07-03)
Asthma is a chronic inflammatory disease that is known to cause changes in the extracellular matrix, including changes in hyaluronan (HA) deposition. However, little is known about the factors that modulate its deposition or the potential consequences. Asthmatics with high...
Cristiane Salum et al.
Neurotoxicity research, 29(1), 92-104 (2015-09-24)
Previous research has shown that nitric oxide (NO) synthase inhibitors prevent rodents' sensorimotor gating impairments induced by dopamine releasing drugs, such as amphetamine (Amph) and methylphenidate. The mechanisms of this effect have not been entirely understood. In the present work...
Hrabie, J.A., et al.
The Journal of Organic Chemistry, 58, 1472-1472 (1993)
Articles
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
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