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F113

Sigma-Aldrich

R(−)-Fenfluramine hydrochloride

Empirical Formula (Hill Notation):
C12H16F3N · HCl
CAS Number:
Molecular Weight:
267.72
MDL number:
PubChem Substance ID:

drug control

USDEA Schedule IV

SMILES string

Cl.CCN[C@H](C)Cc1cccc(c1)C(F)(F)F

InChI

1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H/t9-;/m1./s1

InChI key

ZXKXJHAOUFHNAS-SBSPUUFOSA-N

Biochem/physiol Actions

Neurotoxic on prolonged administration or at high dosage; releases serotonin from axon terminals by a nonexocytotic mechanism; anorectic.
Less active enantiomer

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More documents

Quotes and Ordering

Recent studies in the clinical pharmacology of anorectic drugs.
Silverstone, et al.
Recent Adv. Obes. Res., 5, 285-285 (1986)
Re: Estimate of deaths due to valvular insufficiency attributable to the use of benfluorex in France.
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Pharmacoepidemiology and drug safety, 21(6), 584-585 (2012-04-21)
Benfluorex-induced cardiac valve injury.
Jean Acar
Pharmacoepidemiology and drug safety, 21(11), 1243-1244 (2012-10-31)
Top adviser at the European Medicines Agency quits suddenly.
Paul Benkimoun
BMJ (Clinical research ed.), 344, e2641-e2641 (2012-04-13)
Laurent Savale et al.
The European respiratory journal, 40(5), 1164-1172 (2012-04-24)
Benfluorex was marketed in France until 2009, despite its similar pharmacological properties with fenfluramine and its derivatives known to be a cause of pulmonary arterial hypertension (PAH). The aim of this study is to report clinical and haemodynamic characteristics for

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