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G1422

Sigma-Aldrich

Anti-GPR137B (13-25) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):
Anti-G protein-coupled receptor 137B, Anti-TM7SF1

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~46 kDa

species reactivity

human

technique(s)

western blot: 1:500-1:2,000

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... GPR137B(7107)

General description

G Protein-Coupled Receptor belongs to the largest known receptor family. It is characterized by seven transmembrane domains with an extracellular N terminus and a cytoplasmic C terminus domain. They are further divided into distinct subfamilies depending on their different types of ligands and according to sequence homologies. GPR137B is an integral lysosome membrane protein responsible for tissue-specific expression. It is highly expressed in liver, kidney, heart, brain and placenta.

Immunogen

synthetic peptide corresponding to amino acids 13-25 of human GPR137B.

Application

Anti-GPR137B (13-25) antibody is suitable for western blot at a dilution of 1:500-1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Biochem/physiol Actions

G Protein-Coupled Receptor involves with various extracellular signals such as photons, odorants, biogenic amines, peptides, hormone proteins, proteases, nucleotides. It acts in signal transduction across lysosome membrane.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Certificate of Analysis

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Certificate of Origin

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