G5269

Sigma-Aldrich

D-Glucuronic acid

≥98% (GC)

Synonym(s):
Glucosiduronic acid
Empirical Formula (Hill Notation):
C6H10O7
CAS Number:
Molecular Weight:
194.14
Beilstein/REAXYS Number:
1727083
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

biological source

synthetic (organic)

assay

≥98% (GC)

form

powder

optical activity

[α]/D 35 to 37°, c = 6% (w/v) in H2O (equilibrium value)

application(s)

gas chromatography (GC): suitable

mp

159-161 °C (lit.)

solubility

H2O: soluble 100 mg/mL, clear to slightly hazy

SMILES string

O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O

InChI

1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2-,3+,4-,6+/m0/s1

InChI key

AEMOLEFTQBMNLQ-QIUUJYRFSA-N

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General description

Glucuronic acid is one of the component of xylan backbone, a hemicellulose present in plant cell wall.

Application

D-Glucuronic acid has been used:
  • in in vitro human digestion model
  • as a fibrous cellulose powder, to test the feeding preference among experimental termites
  • as a standard to quantify glucuronic acid in urine sample

Packaging

10, 25, 50, 100 g in poly bottle
10 mg in glass bottle

Biochem/physiol Actions

In humans, glucuronic acid conjugation with steroidal compounds and drugs is an important step in phase II metabolic reactions. This influences the biotransformation process of the compound.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

P Doig et al.
Infection and immunity, 55(6), 1517-1522 (1987-06-01)
The alginate produced by Pseudomonas aeruginosa has been reported to play a role in the adhesion of this bacterium to epithelial cell surfaces, although some controversy concerning this role exists. To clarify this controversy, we investigated the ability of alginate...
Some organic acids acting as stimulants of recruitment and feeding for the Formosan subterranean termite (Isoptera: Rhinotermitidae)
Morales-Ramos JA, et al.
Sociobiology, 54(3), 861-861 (2011)
Plant secondary metabolites compromise the energy budgets of specialist and generalist mammalian herbivores
Sorensen JS, et al.
Ecology, 86(1), 125-139 (2005)
J R Alonso-Fernandez et al.
Journal of clinical laboratory analysis, 24(2), 106-112 (2010-03-25)
We describe the history and current implementation of an inexpensive thin layer chromatography (TLC) method, vertical sandwich-type continuous/evaporative TLC with fixed mobile phase volume, that is convenient for detecting and identifying reducing sugars of clinical relevance in the paper-borne blood...
Use of LC-MS/MS for the open detection of steroid metabolites conjugated with glucuronic acid
Fabregat A, et al.
Analytical Chemistry, 85(10), 5005-5014 (2013)
Articles
Drug conjugate analysis and the enzymatic hydrolysis of glucuronides
Read More

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