H4126

Sigma-Aldrich

Hydrocortisone 21-acetate

≥98% (HPLC)

Synonym(s):
17-Hydroxycorticosterone 21-acetate, 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-acetate, 21-Acetoxy-4-pregnene-11β,17α-diol-3,20-dione, 17-α-Hydroxycorticosterone acetate, 4-Pregnene-11β,17α,21-triol-3,20-dione 21-acetate
Empirical Formula (Hill Notation):
C23H32O6
CAS Number:
Molecular Weight:
404.50
Beilstein/REAXYS Number:
2066841
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

sterility

non-sterile

assay

≥98% (HPLC)

form

powder

application(s)

permeability assay: suitable

mp

223 °C (dec.) (lit.)

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O

InChI

1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1

InChI key

ALEXXDVDDISNDU-JZYPGELDSA-N

Gene Information

Looking for similar products? Visit Product Comparison Guide

General description

Hydrocortisone 21-acetate is an adrenocortical steroid. Hydrocortisone acts as an immunosuppressive drug and might suppress systemic inflammatory responses. It is used to treat rheumatoid arthritis and adrenal insufficiency. It also functions as an antiallergic agent.

Packaging

1, 5, 10 g in glass bottle

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

hazcat

Repr. 1B - STOT RE 2

storage_class_code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Hydrocortisone and cortisone injected into arthritic joints: comparative effects of and use of hydrocortisone as a local antiarthritic agent
Hollander JL, et al.
Journal of the American Medical Association, 147(17), 1629-1635 (1951)
Adrenal insufficiency in patients with cirrhosis and septic shock: effect of treatment with hydrocortisone on survival
Fernandez J, et al.
Hepatology, 44(5), 1288-1295 (2006)
The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies, 20-26 (2014)
Principles of Orthomolecularism, 20-26 (2004)
Differential anti-inflammatory effects of immunosuppressive drugs: cyclosporin, rapamycin and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production
Attur MG, et al.
Inflammation Research, 49(1), 20-26 (2000)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service