Anti-A1CF antibody produced in rabbit

enhanced validation

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Anti-ACF65, Anti-ASP, Anti-ACF64, Anti-ACF, Anti-APOBEC1CF
Human Protein Atlas Number:

biological source


Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies



product line

Prestige Antibodies® Powered by Atlas Antibodies


buffered aqueous glycerol solution

species reactivity



antibody small pack of 25 μL

enhanced validation

orthogonal RNAseq
orthogonal RNAseq
Learn more about Antibody Enhanced Validation


immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:200-1:500

immunogen sequence




UniProt accession no.

shipped in

wet ice

storage temp.


Gene Information

human ... A1CF(29974)

General description

A1CF (apobec-1 complementation factor) codes for apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (APOBEC1). It is a member of the heterogeneous nuclear ribonucleoproteins (hnRNP) family. A1CF has three non-identical RNA recognition motifs (RRM) and a unique C-terminal auxiliary domain.


APOBEC1 complementation factor

Biochem/physiol Actions

A1CF (apobec-1 complementation factor) modulates expression of the gene by regulating the constancy of mRNA and RNA editing. It plays a vital role in the synthesis of ApoB (both isoforms ApoB-48 and ApoB-100). Overexpression of APOBEC-1 in transgenic animals results in liver dysplasia.

Features and Benefits

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.


Corresponding Antigen APREST80274.

Physical form

Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

Legal Information

Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3? untranslated region in MCF7 cells.
Yan X, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(6), 1010428317706218-1010428317706218 (2017)
Identification of a novel variant of the RET proto-oncogene in a novel family with Hirschsprung?s disease.
Kawano T, et al.
Pediatric Surgery International, 33(10), 1041-1046 (2017)
Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout.
Rasheed H, et al.
Arthritis Research & Therapy, 19(1), 161-161 (2017)
A Chester et al.
Biochimica et biophysica acta, 1494(1-2), 1-13 (2000-11-10)
RNA editing is a post-transcriptional process that changes the informational capacity within the RNA. These processes include alterations made by nucleotide deletion, insertion and base conversion. A to I and C to U conversion occurs in mammals and these editing...

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