I9531

Sigma-Aldrich

Imiloxan hydrochloride

>98% (HPLC), solid

Synonym(s):
RS 21361, 2-[(2,3-dihydro-1,4-benzodioxin-2yl)methyl]-1-ethyl-1H-imidazole hydrochloride
Empirical Formula (Hill Notation):
C14H16N2O2 · HCl
CAS Number:
Molecular Weight:
280.75
MDL number:
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

assay

>98% (HPLC)

form

solid

color

white

solubility

H2O: soluble 30 mg/mL

SMILES string

Cl[H].CCn1ccnc1CC2COc3ccccc3O2

InChI

1S/C14H16N2O2.ClH/c1-2-16-8-7-15-14(16)9-11-10-17-12-5-3-4-6-13(12)18-11;/h3-8,11H,2,9-10H2,1H3;1H

InChI key

ANDJPJNFVJXEKX-UHFFFAOYSA-N

Gene Information

human ... ADRA2B(151)

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Selective α2B-adrenoceptor antagonist.

Features and Benefits

This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

3

Certificate of Analysis
Certificate of Origin
Fatih İlkaya et al.
Pharmacology, biochemistry, and behavior, 122, 1-6 (2014-03-04)
It has been shown that imipramine, a tricyclic antidepressant (TCA), is a potent analgesic agent. However, the effect of imipramine on visceral pain has not been extensively investigated. In the current study, our aim was to characterise the putative analgesic...

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