≥98% (TLC)

Tomelukast, 5-[4-(4-Acetyl-3-hydroxy-2-propylphenoxy)butyl]-1H-tetrazole
Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.


≥98% (TLC)

SMILES string




InChI key



5 mg in glass bottle

Biochem/physiol Actions

Selective leukotriene D4 (LTD4) receptor antagonist; PPARα and PPARγ agonist.


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Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Kirsten Scholz-Pedretti et al.
Journal of the American Society of Nephrology : JASN, 13(3), 611-620 (2002-02-22)
Natural activators of peroxisome proliferator-activated receptors (PPAR) are lipid metabolites, including those produced by phospholipases A(2) (PLA(2)). In glomerular mesangial cells, the secreted group IIA PLA(2) (sPLA(2)-IIA), which is thought to be a crucial factor in pathologic processes in the...
J M Peters et al.
Molecular pharmacology, 50(1), 67-74 (1996-07-01)
Peroxisome proliferator-activated receptor alpha (PPAR alpha) mediates the effects of foreign chemical peroxisome proliferators on liver and kidney, including the induction of peroxisomal, mitochondrial, and microsomal enzymes involved in beta-oxidation of fatty acids. However, the role of this receptor in...
J P Patel et al.
Critical care medicine, 23(2), 231-237 (1995-02-01)
Both thromboxane A2 and peptide leukotrienes D4/E4 have been implicated in the pathophysiology of circulatory shock. In the present study, we evaluated the effect of thromboxane A2 and leukotriene D4/E4 receptor antagonism in circulatory shock. Prospective, randomized, controlled trial. Research...
Common structural requirements for peroxisome proliferation by tetrazole and carboxylic acid-containing compounds.
P I Eacho et al.
Annals of the New York Academy of Sciences, 804, 387-402 (1996-12-27)
T S Rao et al.
The Journal of pharmacology and experimental therapeutics, 269(3), 917-925 (1994-06-01)
Intraperitoneal administration of zymosan to mice resulted in marked biosynthesis of eicosanoids and influx of neutrophils with distinct time course profiles. 6-Keto-prostaglandin-F1 alpha (6-KPA) increased between 30 and 60 min and rapidly decreased thereafter. Leukotriene (LT)C4 levels showed similar patterns...

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