L7875

Sigma-Aldrich

DL-Leucine

≥99% (HPLC)

Synonym(s):
(±)-Amino-4-methylpentanoic acid
Linear Formula:
(CH3)2CHCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
Beilstein/REAXYS Number:
636005
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

Quality Level

assay

≥99% (HPLC)

form

powder

application(s)

detection: suitable
peptide synthesis: suitable

color

white

mp

293-296 °C (subl.) (lit.)

solubility

1 M HCl: soluble

SMILES string

CC(C)CC(N)C(O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)

InChI key

ROHFNLRQFUQHCH-UHFFFAOYSA-N

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Application

DL-Leucine is a racemic mixture of the D- and L- enantiomers of Leucine. DL-Leucine is used to form benzimidazole and pyrimidine hydroxy azo dyes with various transition metals. DL-Leucine may be used for the evaluation of chiral amino acid separation techniques.

DL-Leucine is used for the following applications:
  • Used as a standard for the measurement of free amino acids
  • Used in the process of tritiated leucine uptake
  • Used in solution preparation (various organics were used in different combinations and concentrations to model complex surface tension effects, DL-Leucine is one of them). It is chosen due to its presence in atmospheric aerosols and ice nucleation activity as well as for its surfactant character

Packaging

25, 100 g in poly bottle

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

H Chang et al.
British journal of haematology, 111(1), 146-156 (2000-11-25)
Transfusion-associated graft-versus-host disease (TA-GVHD) is usually a fatal outcome of blood transfusion therapy, caused by viable leucocytes contained in the donor blood. Most cases of TA-GVHD occur when less than 4-d-old blood is transfused. We therefore examined the molecular changes...
Modeling the surface tension of complex, reactive organic-inorganic mixtures.
A. N. Schwier et al.
Atmospheric Chemistry and Physics, 13, 10721-10732 (2013)
L Sallami et al.
Journal of dairy science, 87(6), 1585-1594 (2004-09-30)
The effect of incorporating a highly autolytic strain (Lactobacillus delbrueckii subsp. bulgaricus UL12) a proteolytic strain (Lactobacillus casei subsp. casei L2A), or a nisin Z-producing strain (Lactococcus lactis, subsp. lactis biovar diacetylactis UL719) into Cheddar cheese starter culture (Lactococcus lactis...
Masaki Kajimoto et al.
American journal of physiology. Heart and circulatory physiology, 309(7), H1157-H1165 (2015-08-02)
Nutritional energy support during extracorporeal membrane oxygenation (ECMO) should promote successful myocardial adaptation and eventual weaning from the ECMO circuit. Fatty acids (FAs) are a major myocardial energy source, and medium-chain FAs (MCFAs) are easily taken up by cell and...
Farid Ichou et al.
Journal of mass spectrometry : JMS, 49(6), 498-508 (2014-06-11)
Reproducibility among different types of excitation modes is a major bottleneck in the field of tandem mass spectrometry library development in metabolomics. In this study, we specifically evaluated the influence of collision voltage and activation time parameters on tandem mass...

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