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L9625

Sigma-Aldrich

Leu-Gly

Synonym(s):
Leucylglycine
Empirical Formula (Hill Notation):
C8H16N2O3
CAS Number:
Molecular Weight:
188.22
EC Number:
MDL number:
PubChem Substance ID:

assay

≥98% (TLC)

Quality Level

form

powder

color

white

storage temp.

−20°C

SMILES string

CC(C)C[C@H](N)C(=O)NCC(O)=O

InChI

1S/C8H16N2O3/c1-5(2)3-6(9)8(13)10-4-7(11)12/h5-6H,3-4,9H2,1-2H3,(H,10,13)(H,11,12)/t6-/m0/s1

InChI key

LESXFEZIFXFIQR-LURJTMIESA-N

Related Categories

Biochem/physiol Actions

Leucylglycine (Leu-Gly) is used to study the kinetics and speciation of copper(II)- cis, cis-1,3,5-triaminocyclohexane complex-promoted hydrolysis of dipeptides.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. L9625.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Cleavage of L-leucine-containing dipeptides by Clostridium butyricum.
Khelifa N, Brik M, Tessedre AC, et al.
Bioorganic & Medicinal Chemistry, 9, 109-112 (1999)
Yu-Hsin Lin et al.
Nutrients, 10(10) (2018-10-03)
Hot water was used to obtain Chlorella sorokiniana hot water extract (HWE). Subsequently, this byproduct was freeze-dried, hydrolysed at 50 °C using Protease N to obtain C. sorokiniana protein hydrolysates (PN-1), and then digested with a gastrointestinal enzyme (PN-1G). The...
Yu-Hsin Lin et al.
Nutrients, 11(6) (2019-06-19)
This research focuses on cobia skin hydrolysates and their antihypertensive effects via the inhibitory activities of angiotensin I-converting enzyme (ACE). Marine fish Cobia (Rachycentron canadum) skin was hydrolysed for 5 h using Protamex and Protease N to obtain the cobia...
Yuki Fujii et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 7(7-8), 843-851 (2002-08-31)
The hydrolysis of glycylglycine (GylGly), glycyl-L-leucine (GlyLeu), L-leucylglycine (LeuGly) and glycyl-DL-serine (GlySer) promoted by a copper(II)- cis, cis-1,3,5-triaminocyclohexane complex [Cu(II)TACH] was investigated at 70 degrees C and pH 7-10, using HPLC. The observed pseudo-first-order rate constants (k(obs)) and rate enhancing...
Irene L Gutiérrez et al.
Molecular neurobiology, 55(10), 7872-7885 (2018-02-27)
The decline in brain noradrenaline levels is associated with the progression of certain neurodegenerative diseases. This seems to be due, at least in part, to the ability of noradrenaline to limit glial activation and to reduce the damage associated with...

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