All Photos(1)

M0171

Sigma-Aldrich

1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide

Synonym(s):
MQAE, (6-Methoxyquinolinio)acetic acid ethyl ester bromide
Empirical Formula (Hill Notation):
C14H16BrNO3
CAS Number:
Molecular Weight:
326.19
MDL number:
PubChem Substance ID:

mp

177-179 °C (lit.)

storage temp.

2-8°C

SMILES string

[Br-].CCOC(=O)C[n+]1cccc2cc(OC)ccc12

InChI

1S/C14H16NO3.BrH/c1-3-18-14(16)10-15-8-4-5-11-9-12(17-2)6-7-13(11)15;/h4-9H,3,10H2,1-2H3;1H/q+1;/p-1

InChI key

DSLLHVISNOIYHR-UHFFFAOYSA-M

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Application

Chloride probe

Certificate of Analysis

Certificate of Origin

A S Verkman
The American journal of physiology, 259(3 Pt 1), C375-C388 (1990-09-01)
Chloride movement across cell plasma and internal membranes, is of central importance for regulation of cell volume and pH, vectorial salt movement in epithelia, and, probably, intracellular traffic. Quinolinium-based chloride-sensitive fluorescent indicators provide a new approach to study chloride transport
A S Verkman et al.
Analytical biochemistry, 178(2), 355-361 (1989-05-01)
A class of N-substituted quinoline compounds has been introduced recently for the fluorescence measurement of Cl concentration in biological preparations. The most Cl-sensitive compound was 6-methoxy-N-[3-sulfopropyl] quinolinium with peak excitation and emission wavelengths of 350 and 442 nm and a
Irene Joy I dela Peña et al.
The American journal of Chinese medicine, 43(4), 667-679 (2015-06-30)
The Artemisia group of plants has long been used as a traditional remedy for various conditions. The present study assessed the sleep-promoting (sedative-hypnotic) effects of Artemisia capillaris Thunberg (A. capillaris), and elucidated a possible mechanism behind its effect. ICR mice
Daniel DeWoskin et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(29), E3911-E3919 (2015-07-02)
The suprachiasmatic nuclei (SCN), the central circadian pacemakers in mammals, comprise a multiscale neuronal system that times daily events. We use recent advances in graphics processing unit computing to generate a multiscale model for the SCN that resolves cellular electrical
Vikash Kumar Shah et al.
Biomolecules & therapeutics, 22(4), 314-320 (2014-08-22)
This study was investigated to know whether pachymic acid (PA), one of the predominant triterpenoids in Poria cocos (Hoelen) has the sedative-hypnotic effects, and underlying mechanisms are mediated via γ-aminobutyric acid (GABA)-ergic systems. Oral administration of PA markedly suppressed locomotion

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