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M4262

Sigma-Aldrich

3′-O-Methyluridine

Empirical Formula (Hill Notation):
C10H14N2O6
CAS Number:
Molecular Weight:
258.23
MDL number:
PubChem Substance ID:

form

solid

storage temp.

−20°C

SMILES string

COC1C(O)C(OC1CO)N2C=CC(=O)NC2=O

InChI

1S/C10H14N2O6/c1-17-8-5(4-13)18-9(7(8)15)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)

InChI key

YKNATSNMFLEFRB-UHFFFAOYSA-N

Application

3′-O-Methyluridine may be used in comparative studies on the methylation of 2′ and 3′ hydroxyl groups of uridines in plant microRNAs.

Certificate of Analysis

Certificate of Origin

Qingchun Zhang et al.
Journal of the American Society for Mass Spectrometry, 17(8), 1096-1099 (2006-06-06)
Recent studies revealed that the 3'-terminal nucleotides in plant microRNAs were methylated on the ribose at the 2' or 3' hydroxyl groups. Here we examined the fragmentation of the electrospray-produced [M + H]+ and [M - H]- ions of 2'-

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