Matthew J Culyba et al.
PLoS genetics, 14(6), e1007405-e1007405 (2018-06-02)
Biochemical pathways are often genetically encoded as simple transcription regulation networks, where one transcription factor regulates the expression of multiple genes in a pathway. The relative timing of each promoter's activation and shut-off within the network can impact physiology. In...
Intestinimonas butyriciproducens gen. nov., sp. nov., a butyrate-producing bacterium from the mouse intestine.
International Journal of Systematic and Evolutionary Microbiology, 63, 4606-4612 (2013)
David Chen et al.
Molecular systems biology, 8, 620-620 (2012-10-24)
Natural biological systems have evolved a diverse array of switches to realize their strategies for environmental response and development. Emerging applications of synthetic biology have begun to exploit such switches to achieve increasingly sophisticated designed behaviors. However, not all switch...
An expanded genetic code with a functional quadruplet codon.
Proceedings of the National Academy of Sciences of the USA, 101(20) (2004)
Lauren B A Woodruff et al.
Nucleic acids research, 45(3), 1553-1565 (2016-12-23)
Genetic designs can consist of dozens of genes and hundreds of genetic parts. After evaluating a design, it is desirable to implement changes without the cost and burden of starting the construction process from scratch. Here, we report a two-step...