Proteinase 3 is a phosphatidylserine binding protein which affects the production and function of microvesicles
Martin KR, et al.
The Journal of biological chemistry, jbc-M115 (2016)
Y M van der Geld et al.
Journal of leukocyte biology, 69(2), 177-190 (2001-03-29)
Proteinase 3 (PR3) is one of four serine protease homologues in the azurophilic granules of neutrophils and granules of monocytes. It is of importance that anti-neutrophil cytoplasmic antibodies (ANCA) in patients with Wegener's granulomatosis (WG) are mainly directed against PR3...
Genetics and pathophysiology of granulomatosis with polyangiitis (GPA) and its main autoantigen proteinase 3
Relle M, et al.
Molecular and Cellular Probes, 30(6), 366-373 (2016)
Molecular analysis of the membrane insertion domain of proteinase 3, the Wegener?s autoantigen, in RBL cells: implication for its pathogenic activity
Kantari C, et al.
Journal of Leukocyte Biology, 90(5), 941-950 (2011)
M M Boomsma et al.
Journal of immunological methods, 254(1-2), 47-58 (2001-06-19)
The prevalence of Anti-Neutrophil Cytoplasmic Antibodies (ANCA) directed against myeloperoxidase (MPO) in pauci-immune necrotizing crescentic glomerulonephritis (NCGN) is dependent on the assay(s) used. We investigated the frequency of MPO-ANCA as detected by different assays for MPO-ANCA in a large cohort...