All Photos(1)

P2342

Sigma-Aldrich

1,2-Didocosanoyl-sn-glycero-3-phosphocholine

≥99% (TLC)

Synonym(s):
L-α-Phosphatidylcholine, dibehenoyl
Empirical Formula (Hill Notation):
C52H104NO8P
CAS Number:
Molecular Weight:
902.36
MDL number:
PubChem Substance ID:

assay

≥99% (TLC)

functional group

phospholipid

shipped in

ambient

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C52H105NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-51(54)58-48-50(49-60-62(56,57)59-47-46-53(3,4)5)61-52(55)45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h50H,6-49H2,1-5H3,(H,56,57)

InChI key

AJOVBBNZJBGJAP-UHFFFAOYSA-N

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Certificate of Analysis

Certificate of Origin

Eric C Abenojar et al.
Pharmaceutics, 12(3) (2020-03-04)
The amount of gas in ultrasound contrast agents is related to their acoustic activity. Because of this relationship, gas volume has been used as a key variable in normalizing the in vitro and in vivo acoustic behavior of lipid shell-stabilized...
Jinhui Gao et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 157, 233-240 (2020-11-24)
Survival rates in pancreatic cancer have remained largely unchanged over the past four decades with less than 5% of patients surviving five years following initial diagnosis. FOLFIRINOX chemotherapy, a combination of folinic acid, 5-fluoruracil, irinotecan and oxaliplatin, has shown the...
Dario Carugo et al.
Biomaterials, 113, 105-117 (2016-11-05)
The transfer of material from phospholipid-coated microbubbles to cell membranes has been hypothesized to play a role in ultrasound-mediated drug delivery. In this study, we employed quantitative fluorescence microscopy techniques to investigate this phenomenon in both artificial and biological membrane...
Carly Pellow et al.
Theranostics, 10(25), 11690-11706 (2020-10-15)
Background: There has been growing interest in nanobubbles for their potential to extend bubble-mediated ultrasound approaches beyond that of their larger microbubble counterparts. In particular, the smaller scale of nanobubbles may enable them to access the tumor extravascular compartment for...
Bingbing Cheng et al.
Ultrasound in medicine & biology, 45(8), 2174-2187 (2019-05-11)
Real-time acoustic feedback control based on harmonic emissions of stimulated microbubbles may serve as a way to achieve reliable blood-brain barrier (BBB) opening with focused ultrasound in the brain. Previously, we demonstrated BBB opening was possible using sub-micron bubbles (aka...

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