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P5648

Sigma-Aldrich

β-Propiolactone

Grade II, ≥90%

Synonym(s):
Oxetan-2-one, 3-Hydroxypropionic acid lactone, Hydracrylic acid β-lactone
Empirical Formula (Hill Notation):
C3H4O2
CAS Number:
Molecular Weight:
72.06
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

type

Grade II

Quality Level

assay

≥90%

refractive index

n20/D 1.412 (lit.)

bp

162 °C (lit.)

mp

−33 °C (lit.)

density

1.146 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

O=C1CCO1

InChI

1S/C3H4O2/c4-3-1-2-5-3/h1-2H2

InChI key

VEZXCJBBBCKRPI-UHFFFAOYSA-N

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General description

β-Propiolactone is an alkylating agent which is mainly used in veterinary vaccines. It will not interfere with the antigenicity of vaccine.

Application

β-Propiolactone has been used for Influenza virus deactivation.

Packaging

1, 5, 10, 50, 100 mL in glass bottle

Caution

Insoluble polymers may form during storage.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Inhalation - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

158.0 °F - closed cup

Flash Point(C)

70 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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