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PEPTIDE

Sigma-Aldrich

Custom Peptides

Product Overview, Design, and Ordering

Synonym(s):
peptide array, Isotopically labeled peptide, PEPscreen, peptide library, peptide microarray, AQUA peptide


Custom Peptides

  • High quality peptide synthesis using FMOC and/or BOC chemistries
  • Sequence length: 2-40mer
  • Amount: up to 1 gram
  • Purity Levels: Unpurified, 70%, 80%, 95%
  • Comprehensive Modification offering including, FRET, C-terminal aldehyde, phosphorylation, multiple disulfide bonds, etc.
  • Format: Supplied lyophilized
  • QC Analysis: All peptides by HPLC and MS; additional analysis available upon request
  • Learn more

PEPscreen®: Custom Peptide Libraries

  • Suitable for robotic production of peptide microarrays
  • Screen mulitple proteotyptic peptides and rapidly characterize and select mass spec compatible peptides
  • Get results quick with delivery of your peptide library in less than 7 business days
  • Sequence Length: 6 to 20 amino acids
  • Amount: 0.5-2mg or 2-5mg
  • Modifications:  Comprehensive offering including phosphorylation, biotin, fluorescein, stable isotopes, etc.
  • Format: Supplied dry in a 96 well tube rack
  • Options: Normalization and aliquoting (stock and copy libraries)
  • Minimum library size of 24 peptides
  • Learn more

AQUA™ Peptides

  • Accurately quantitate low abundance proteins
  • Measure site-specific phosphorylation states
  • Validate gene silencing at the protein level
  • Custom peptides are available either without stable isotope labeling, or with stable isotope labeling
  • Stable-isotope labeled AQUA™ Peptide seqeunces contain one isotopically labeled amino acid
  • Sequence Length: 5 to 30 amino acids
  • Amount: 5 x 1 nmole
  • Purity: >95% by RP-HPLC
  • Modifications: phosphorylation (Ser, Thr, Tyr), carboxymethylated Cys, carbamidomethylated Cys, hydroxyproline, N-terminal biotin (please inquire regarding other modifications)
  • Quantification by amino acid analysis (AAA)
  • Format: Supplied dry
  • Learn more

Lilian Aly et al.
Brain : a journal of neurology, 134(Pt 9), 2687-2702 (2011-09-13)
Progressive multi-focal leucoencephalopathy and progressive multi-focal leucoencephalopathy-immune reconstitution inflammatory syndrome are caused by infection of the central nervous system with the JC polyoma virus. Both are complications of monoclonal antibody therapy in multiple sclerosis and other autoimmune diseases. Progressive multi-focal...
James F Guenther et al.
The Plant cell, 15(4), 981-991 (2003-04-03)
Soybean nodulin 26 is expressed and targeted to the symbiosome membrane of nitrogen-fixing nodules, where it forms an aquaporin channel with a modest water transport rate. In this study, we show that the phosphorylation of nodulin 26 on Ser-262, which...
Virginie Brun et al.
Molecular & cellular proteomics : MCP, 6(12), 2139-2149 (2007-09-13)
Diagnostic development and public health surveillance require technologies that provide specific identification and absolute quantification of protein biomarkers. Beside immunologically related techniques (e.g. enzyme-linked immunosorbent assay), MS is gaining increasing interest due to its high sensitivity and specificity. Furthermore, MS-based...
Wolfgang Hueber et al.
Arthritis research & therapy, 11(3), R76-R76 (2009-05-23)
Anti-TNF therapies have revolutionized the treatment of rheumatoid arthritis (RA), a common systemic autoimmune disease involving destruction of the synovial joints. However, in the practice of rheumatology approximately one-third of patients demonstrate no clinical improvement in response to treatment with...
Magdalena Banas et al.
PloS one, 8(3), e58709-e58709 (2013-03-26)
Chemerin, a chemoattractant ligand for chemokine-like receptor 1 (CMKLR1) is predicted to share similar tertiary structure with antibacterial cathelicidins. Recombinant chemerin has antimicrobial activity. Here we show that endogenous chemerin is abundant in human epidermis, and that inhibition of bacteria...
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Custom PEPscreen Peptide Libraries
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We synthesize peptides up to 200 amino acids in length using state of the art solid support chemistries and purify peptides using HPLC. A variety of purity levels, scales of synthesis and extensive modifications are available.
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Affordable and fast delivery of custom peptide libraries for target identification. The PEPscreen® peptide library is configured in a convenient plate format, perfect for screening applications, epitope mapping and peptide microarray production.
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