≥75% α-anomer basis
white to light yellow
121 °C (dec.) (lit.)
DNA synthesis | interferes
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UN 3077 9 / PGIII
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
Streptozocin should be stored at -20 degrees C with desiccation. The desiccant is to prevent moisture uptake which can shorten shelf-life.
Aqueous solutions rapidly undergo mutarotation to an equilibrium mixture of alpha- and beta-anomers. Maximum solution stability is at pH 4, with stability decreasing rapidly at higher or lower pH. Freshly prepared solutions are clear and have a light straw color. On standing, they take on a yellow to brown color and effervesce, indicating decomposition. Solutions should be prepared just before use, since the product is unstable.
Streptozocin has a reported half life of 15 to 30 minutes.
This product dissolves in water at 50 mg/mL to give a light yellow solution, from clear to slightly hazy. We recommend using a 20 mM citrate buffer at pH 4.5 for best solution stability.
We do not test Streptozocin, Product No. S0130 for biological activity. We recommend screening lots for biological activity. An intravenous injection of streptozocin into rats at a dose of 65 mg/kg body weight to induce diabetes has been reported by Burcelin R. et al. in Biochem. J., 291, 109-113 (1993).
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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