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≥98% (HPLC), powder

Gabazine, 2-(3-Carboxypropyl)-3-amino-6-(4 methoxyphenyl)pyridazinium bromide
Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:

Quality Level


≥98% (HPLC)






H2O: >10 mg/mL

SMILES string




InChI key



10, 50 mg in glass bottle

Biochem/physiol Actions

SR-95531 is a specific GABAA receptor antagonist that does not affect GABA-transaminase or glutamate-decarboxylase activities.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at
This compound is featured on the GABAA Receptors and GABAC Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

13 - Non Combustible Solids

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Le Chang et al.
Neuron, 77(3), 559-571 (2013-02-12)
Retinal specializations such as cone-photoreceptor opsin-expression gradients, as found in several vertebrate species, are intuitively considered detrimental to color vision. In mice, the majority of cones coexpress both "blue" and "green" opsin. The coexpression ratio changes along the dorsoventral axis...
Ian Duguid et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(32), 11132-11143 (2012-08-10)
Tonic inhibition is a key regulator of neuronal excitability and network function in the brain, but its role in sensory information processing remains poorly understood. The cerebellum is a favorable model system for addressing this question as granule cells, which...
Marvin R Diaz et al.
PloS one, 8(1), e55673-e55673 (2013-02-06)
Cerebellar granule cells (CGNs) are one of many neurons that express phasic and tonic GABAergic conductances. Although it is well established that Golgi cells (GoCs) mediate phasic GABAergic currents in CGNs, their role in mediating tonic currents in CGNs (CGN-I(tonic))...
G C Gregoriou et al.
Molecular pharmacology, 98(4), 454-461 (2020-07-02)
Endogenous opioid peptides in the amygdala regulate many of our behaviors and emotional responses. In particular, the endogenous opioid enkephalin plays a significant role in regulating amygdala activity, but its action is strongly limited by peptidases, which degrade enkephalin into...
Daniel A Llano et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(46), 16141-16148 (2012-11-16)
Flavoprotein autofluorescence imaging was used to examine auditory cortical synaptic responses in aged animals with behavioral evidence of tinnitus and hearing loss. Mice were exposed to noise trauma at 1-3 months of age and were assessed for behavioral evidence of...

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