S3547

Sigma-Aldrich

Sesame oil

Antioxidant, delivery vehicle for fat-soluble compounds

CAS Number:
EC Number:
MDL number:
NACRES:
NA.25

biological source

Sesamum indicum (sesame)

Quality Level

form

liquid

density

0.92 g/mL at 25 °C

functional group

oleic acid

shipped in

ambient

storage temp.

room temp

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General description

Sesame oil may be used in the production of biodiesel and may serve as a viable alternative for the diesel fuel. It acts as an antioxidant having neuroprotective activity on brain hippocampus of rat in focal cerebral ischemia, when given as a dietary supplement. Consumption of sesame oil has a beneficial effect on blood glucose, glycosylated hemoglobin, lipid peroxidation, and antioxidant levels in diabetic rats.

Application

Sesame oil is suitable:
  • for dissolving free testosterone
  • for the preparation of tamoxifen i.p. injection
  • for dissolving aromatizable androgen testosterone and non-aromatizable androgen 5α-dihydrotestosterone
  • as a delivery vehicle for the injection of estradiol benzoate
  • for dissolving progesterone and estradiol-17β
  • for dissolving semisynthetic form of acetyl-11-keto-β-boswellic acid
Used in research applications as delivery vehicle for fat-soluble compounds including steroidal hormones and toxins. Sesame oil has antioxidant properties and was shown to protect against lipopolysaccharide (LPS)-stimulated oxidative stress in animal models.

Packaging

1 L in glass bottle
250 mL in glass bottle

Certificate of Analysis

Certificate of Origin

Saif Ahmad et al.
Life sciences, 79(20), 1921-1928 (2006-07-11)
Oxidative stress may be regarded as an imbalance between free radical production and opposing antioxidant defenses. Free radical oxidative stress is implicated in rat cerebral ischemia and naturaceutical antioxidants are dietary supplements that have been reported to have neuroprotective activity....
Abdurrahman Saydut et al.
Bioresource technology, 99(14), 6656-6660 (2008-01-08)
The sesame (Sesamum indicum L.) oil was extracted from the seeds of the sesame that grows in Diyarbakir, SE Anatolia of Turkey. Sesame seed oil was obtained in 58wt/wt%, by traditional solvent extraction. The methylester of sesame (Sesamum indicum L.)...
Milos Lazic et al.
The Journal of endocrinology, 208(3), 293-300 (2010-12-22)
Prenatal androgen produces many reproductive and metabolic features of polycystic ovary syndrome in female rodents, sheep, and monkeys. We investigated the impact of such prenatal treatment in adult male rats. Pregnant dams received free testosterone (T; aromatizable androgen), dihydrotestosterone (D;...
Marek Demissie et al.
American journal of physiology. Endocrinology and metabolism, 295(2), E262-E268 (2008-06-12)
Androgen exposure during intrauterine life in nonhuman primates and in sheep results in a phenocopy of the reproductive and metabolic features of polycystic ovary syndrome (PCOS). Such exposure also results in reproductive features of PCOS in rodents. We investigated whether...
Justin T Hsieh et al.
Neuroendocrinology, 103(5), 518-530 (2015-09-12)
Preclinical evidence suggests that progesterone improves recovery after intracerebral hemorrhage (ICH); however, gonadal hormones have sex-specific effects. Therefore, an experimental model of ICH was used to assess recovery after progesterone administration in male and female rats. ICH was induced in...

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