S8432

Sigma-Aldrich

Sulfo NONOate disodium salt

Synonym(s):
Hydroxydiazenesulfonic acid 1-oxide disodium salt
Linear Formula:
N2O5SNa2
Molecular Weight:
186.06
MDL number:
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.

form

powder

Quality Level

shipped in

dry ice

storage temp.

−70°C

SMILES string

Na+.Na+.O-\N=N+(/O-)S(O-)(=O)=O

InChI

1S/H2N2O5S.2Na/c3-1-2(4)8(5,6)7;;/h3H,(H,5,6,7);;/q;2*+1/p-2/b2-1+;;

InChI key

LYIIGAIVRHASTQ-SEPHDYHBSA-L

Application

Does not release NO; useful as a negative control in NONOate research

Biochem/physiol Actions

SKI 5C was used to inhibit Sphingosine kinase 1 in SK-Hep1, HEK-293T cells.1

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xi

Risk Statement

36/37/38

Safety Statement

26

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Aneta Balcerczyk et al.
Free radical biology & medicine, 39(3), 327-335 (2005-07-05)
The specificity of 4-amino-5-methylamino-2',7'-difluorofluorescein (DAF-FM) for nitric oxide was evaluated in in vitro systems. The probe was found fairly specific for nitric oxide. Potential sources of artifacts include the autoxidation of DAF-FM, potentiated by light, and its oxidation by sources...
C M Maragos et al.
Journal of medicinal chemistry, 34(11), 3242-3247 (1991-11-01)
Selected nucleophile/nitric oxide adducts [compounds which contain the anionic moiety, XN(O-)N = O] were studied for their ability to release nitric oxide spontaneously in aqueous solution and for possible vasoactivity. The diversity of structures chosen included those in which the...
Articles
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
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