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Anti-TAU antibody produced in rabbit

affinity isolated antibody

Microtubule-associated protein tau, Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, MAPT
MDL number:

biological source




antibody form

affinity isolated antibody

antibody product type

primary antibodies




buffered aqueous solution

mol wt

antigen 78 kDa

species reactivity

mouse, human, rat


~1 mg/mL


ELISA: 1:20000
western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.


Gene Information

human ... MAPT(4137)

General description

Anti-TAU antibody detects endogenous levels of total TAU protein.
MAPT (microtubule associated protein tau) is located on human chromosome 17q21.3. It is expressed in neurons but is most prominent in axons.


The antiserum was produced against synthesized peptide derived from human Tau.

Immunogen Range: 266-315

Biochem/physiol Actions

Removal of MAPT results in developmental delay and learning disability. It participates in the pathology of Alzheimer′s disease (AD). It helps in the assembly and maintenance of microtubule structure.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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Youssra K Al-Hilaly et al.
Journal of molecular biology, 430(21), 4119-4131 (2018-08-20)
Alzheimer's disease is a tauopathy characterized by pathological fibrillization of tau protein to form the paired helical filaments (PHFs), which constitute neurofibrillary tangles. The methylthioninium (MT) moiety reverses the proteolytic stability of the PHF core and is in clinical development
Microdeletion encompassing MAPT at chromosome 17q21.3 is associated with developmental delay and learning disability
Shaw-Smith C
Nature Genetics, 38(9), 1032-1037 (2006)
Linkage disequilibrium and association of MAPT H1 in Parkinson disease
Skipper L, et al.
American Journal of Human Genetics, 75(4), 669-677 (2004)
The H1c haplotype at the MAPT locus is associated with Alzheimer's disease
Myers AJ, et al.
Human Molecular Genetics, 14(16), 2399-2404 (2005)

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