Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma.
The Journal of Clinical Investigation, 127(10), 3877-3896 (2017)
Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity.
The Journal of Clinical Investigation, 126(7), 2575-2587 (2016)
Angiopoietin-2 and soluble Tie-2 receptor plasma levels in children with obstructive sleep apnea and obesity.
Obesity (Silver Spring, Md.), 25(6), 1083-1090 (2017)
Hisashi Takada et al.
Cancer science, 96(2), 100-110 (2005-02-23)
We performed genome-wide screening for deoxyribonucleic acid copy-number aberrations in 31 gastric cancer (GC) cell lines by using custom-made comparative genomic hybridization (CGH)-array. Copy-number gains were frequently detected at 1q, 3q, 5p, 7p, 7q, 8q, 11q, 17q, 20p, 20q, Xp...
Jaeryung Kim et al.
Science advances, 5(2), eaau6732-eaau6732 (2019-02-23)
Choriocapillary loss is a major cause of neovascular age-related macular degeneration (NV-AMD). Although vascular endothelial growth factor (VEGF) blockade for NV-AMD has shown beneficial outcomes, unmet medical needs for patients refractory or tachyphylactic to anti-VEGF therapy exist. In addition, the...