MYC Is a Crucial Mediator of TGF?-Induced Invasion in Basal Breast Cancer.
Cancer Research, 76(12), 3520-3530 (2016)
Lou-Ella M M Alexander et al.
Molecular immunology, 91, 8-16 (2017-09-01)
B cell activation is dependent on a large increase in transcriptional output followed by focused expression on secreted immunoglobulin as the cell transitions to an antibody producing plasma cell. The rapid transcriptional induction is facilitated by the release of poised...
Tianhe Huang et al.
Nature communications, 11(1), 2124-2124 (2020-05-03)
Penile squamous cell carcinoma (PSCC) accounts for over 95% of penile malignancies and causes significant mortality and morbidity in developing countries. Molecular mechanisms and therapies of PSCC are understudied, owing to scarcity of laboratory models. Herein, we describe a genetically...
Adaptor protein-3: A key player in RBL-2H3 mast cell mediator release.
da Silva EZ
PLoS ONE, 12(3), e0173462-e0173462 (2017)
Hanfang Zhang et al.
Investigative ophthalmology & visual science, 59(6), 2520-2528 (2018-05-31)
Neurofibromatosis type 1 (NF1) is the result of inherited mutations in the NF1 tumor suppressor gene, which encodes the protein neurofibromin. Eye manifestations are common in NF1 with recent reports describing a vascular dysplasia in the retina and choroid. Common...