Vancomycin hydrochloride from Streptomyces orientalis

BioReagent, suitable for plant cell culture

Empirical Formula (Hill Notation):
C66H75Cl2N9O24 · HCl
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
Pricing and availability is not currently available.

Quality Level

biological source

Streptomyces orientalis

product line





≥900 μg per mg

storage condition

(Keep container tightly closed in a dry and well-ventilated place.)


cell culture | plant: suitable


white to orange-brown


H2O: 50 mg/mL, clear, colorless to dark yellow (and Very Faint Orange to Faint Orange)

Featured Industry


Mode of action

cell wall synthesis | interferes

antibiotic activity spectrum

Gram-positive bacteria

storage temp.


SMILES string


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General description

Vancomycin is a heptapeptide.
Chemical structure: glycopeptide


Vancomycin hydrochloride from Streptomyces orientalis has been used as:
  • an antibiotic in screening: minimal inhibitory concentrations (MICs) Streptomyces coelicolor
  • in treating Leishmania infected sand flies
  • in combined antibiotic treatment in asthma induced mice


1, 5 g in glass bottle

Biochem/physiol Actions

Vancomycin is used for treating methicillin-resistant Staphylococcus aureus (MRSA) infections and shunt-associated Staphylococcal ventriculitis. It may lead to hypersensitivity reactions like anaphylaxis and red man syndrome. Vanomycin is also used to treat thrombocytopenia and induces drug reaction with eosinophilia and systemic symptoms (DRESS) on usage.
Glycopeptide antibiotic
Mode of action: Used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis by inhibiting incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides.
Antimicrobial spectrum: Gram-positive bacteria

Other Notes

Keep container tightly closed in a dry and well-ventilated place.


Health hazard

Signal Word


Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

T Asano et al.
Phytopathology, 89(4), 314-319 (2008-10-24)
ABSTRACT Resting spores of Plasmodiophora brassicae were surface-disinfested by treatment with 2% chloramine-T for 20 min and then with an antibiotic solution (1,000 ppm of colistin sulfate, 1,000 ppm of vancomycin hydrochloride, and 6,000 ppm of cefotaxime sodium) for 1...
Vancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Masquerading as Elusive Sepsis
Roy S, et al.
Case reports in immunology, 2019, 119-119 (2019)
Optimization of fermentation conditions for production of glycopeptide antibiotic vancomycin by Amycolatopsis orientalis
Padma PN, et al.
Applied Biochemistry and Biotechnology, 102(1-6), 395-405 (2002)
Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis
Xu L, et al.
BMC Genomics, 15(1), 363-363 (2014)
Early-life antibiotics attenuate regulatory T cell generation and increase the severity of murine house dust mite-induced asthma
Adami AJ, et al.
Pediatric Research, 84(3), 426-426 (2018)
Inhibition of Cell Wall Biosynthesis by Antibiotics
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